Thyroid Hormones in ADPKD

Launched by MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH · Dec 5, 2022

Keywords

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Gender

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Eligibility criteria

• Inclusion Criteria:
• • 1. Male and female ≥18 years old;
• • 2. Diagnosis of ADPKD based on renal ultrasonography or genetic test;
• • 3. Written informed consent
• Exclusion Criteria:
• • 1. Diagnosis of Hashimoto's disease, hyperthyroidism or pituitary disease or any other condition undergoing levothyroxine replacement
• • 2. Patient with hypothyroidism treated with drug therapy
• • 3. Active treatment with Tolvaptan and/or Octreotide-LAR;
• • 4. Regular treatment with amiodarone, lithium, interferon or immunosuppressive drugs including steroids;
• • 5. Active malignancy or acute or chronic inflammatory disease, HIV;
• • 6. Dialysis or kidney transplantation;
• • 7. Diabetes mellitus;
• • 8. Hypocaloric diet or current dietary approaches to obtain weight loss.
• • 9. Legal incapacity or any evidence that the patient will not be able to understand the study aims and procedures.