The Efficacy of L-Carnitine in the Management of Acute Carbon Monoxide Poisoning
Launched by ALEXANDRIA UNIVERSITY · Dec 8, 2022
Trial Information
Current as of January 22, 2025
Unknown status
Keywords
ClinConnect Summary
A randomized clinical trial (phase II) will be conducted at Alexandria Main University Hospital.
The total required sample size is 72. The sample size was calculated by G power 3.1.9.4 software program depending on the primary outcome. According to these assumptions: Effect size, defined as the difference between group 1 and group 2 in the mean troponin levels at 24 hr, was calculated according to Sun et al. (2011) and was 0.657, alpha error =0.05, power of 80%, allocation ratio 1:1. A 20% expected attrition was added to the sample size to account for loss to follow-up. So, the final sampl...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • The current clinical trials will include patients with moderate and severe acute carbon monoxide poisoning according to Poisoning Severity Score.
- Exclusion Criteria:
- • When the diagnosis of acute carbon monoxide poisoning is unconfirmed.
- • Patients with advanced cardiac and neurological diseases.
Trial Officials
Zahraa K Sobh, MD
Principal Investigator
Associate Professor of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Alexandria University, Alexandria, Egypt
Maha A Ghanem, MD
Principal Investigator
Professor of Forensic Medicine and Clinical Toxicology. Head of department of Forensic Medicine and Clinical Toxicology. Chairperson of ethics committee Faculty of Medicine
Heidi A Elsobky, MS
Study Director
Assistant Lecturer of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Alexandria University, Alexandria, Egypt
Farah S Habib, Bachelor
Study Director
Demonstrator of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Alexandria University, Alexandria, Egypt
Fatma Elgazzar, MD
Principal Investigator
Professor of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Tanta University, Alexandria, Egypt
About Alexandria University
Alexandria University, a leading academic institution in Egypt, is dedicated to advancing medical research and improving healthcare outcomes through innovative clinical trials. With a strong emphasis on collaboration and interdisciplinary approaches, the university leverages its extensive resources and expertise to conduct rigorous studies that address pressing health challenges. By fostering partnerships with healthcare professionals, industry leaders, and regulatory bodies, Alexandria University aims to contribute to the global body of medical knowledge and enhance the quality of patient care through evidence-based findings.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
People applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Discussion 0
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