Keywords

ClinConnect Summary

This clinical trial is studying how menopause affects women's heart health over time. After menopause, the body stops producing estrogen, which can lead to a higher risk of heart problems such as hardening of the arteries, heart attacks, and strokes. The researchers will follow 200 women from before they enter menopause and for at least 10 years afterward. They will look closely at changes in the blood vessels, heart, and brain, and analyze blood samples to understand better how menopause influences cardiovascular health.

To be eligible for this study, women should have a normal heart test and regular menstrual cycles. However, there are some exclusions, such as those who smoke, are on hormone therapy, have certain chronic diseases, or are pregnant or breastfeeding. Participants can expect regular check-ups and tests to monitor their health throughout the study. This research aims to provide valuable insights into the connection between menopause and heart disease, which could help improve health strategies for women as they age.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Normal ECG
• • Regular menstruation
• Exclusion Criteria:
• • Participation in other clinical projects
• • Smokes or has smoked within the last 10 years
• • On hormone therapy
• • Has chronic diseases that are not expected, cf. the groups sought. Including heart problems, atrial fibrillation, cancer, immune diseases and previous strokes with functionally significant sequelae
• • Being treated with oral steroids
• • Has alcohol / drug abuse or is being treated with disulfiram (Antabus)
• • Is unable to understand the contents of the document with informed consent or the experimental procedures
• • Pregnancy or breastfeeding
• • Systolic blood pressure ≥140 mmHg and/or diastolic blood pressure ≥90 mmHg
• • ovariectomy
• • BMI\>28

Trial Officials