Association of Asprosin in Periodontitis and Acute Coronary Syndrome
Launched by ATATURK UNIVERSITY · Dec 4, 2022
Trial Information
Current as of August 14, 2025
Completed
Keywords
ClinConnect Summary
Periodontal disease is a chronic, multifactorial, and infectious disease caused by bacteria. It is characterized by the formation of an inflammatory response in the supporting bone and connective tissue against microbial dental plaque, and the nature of the resulting inflammatory response determines the course of periodontal disease. Cardiovascular and periodontal diseases are closely related, presenting a triad association. Asprosin circulates in the blood at nanomolar levels and is taken to the liver, where it activatesinvestigators the G protein-cAMP-PKA pathway, causing rapid glucose re...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • For Healthy group
- • All individuals were generally healthy,
- • non-smoking For Myocard Infarctus group
- • patients with ST elevation of Myocardial Infactus
- • patient with less than ten teeth
- Exclusion Criteria:
- • Smokers or those with diabetes or other inflammatory disease
- • Pregnant or breastfeeding women
- • None had undergone periodontal therapy and/or antibiotic therapy in the past 6 months.
- • None has a contagious disease such as HIV or AIDS
About Ataturk University
Atatürk University, located in Erzurum, Turkey, is a prominent academic institution dedicated to advancing research and education across various disciplines. As a clinical trial sponsor, the university leverages its extensive resources and expertise to facilitate innovative medical research aimed at improving patient outcomes and contributing to the global body of health knowledge. Committed to ethical standards and rigorous scientific methodologies, Atatürk University collaborates with healthcare professionals, researchers, and regulatory bodies to ensure the integrity and efficacy of its clinical trials, ultimately enhancing the quality of care and driving advancements in medical science.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Erzurum, , Turkey
Patients applied
Trial Officials
Oğuzhan Birdal, Asist. Prof.
Study Chair
Ataturk University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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