Comparison of the Effectiveness of Three Different Gargates in Radiotherapy-Associated Oral Mucositis

Launched by SAGLIK BILIMLERI UNIVERSITESI GULHANE TIP FAKULTESI · Dec 11, 2022

Keywords

ClinConnect Summary

The research was conducted as a randomized controlled clinical trial between January 2020 and January 2022. The sample of the research; Patients who applied to Hospital Radiotherapy Unit, received 50-60 Gy radiotherapy in the oral cavity, had a primary diagnosis of head and neck cancer, had no metastasis, had no complaints about mucositis, were older than 18 years old, spoke Turkish, and agreed to participate, in the study. With the closed-envelope randomization method, 48 patients were included in the sample, 12 patients for each of the saline, sodium bicarbonate, thyme honey, and control ...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Primary diagnosis is head and neck cancer
• • To be receiving radiotherapy at a dose of 50-60 Gy in the oral cavity
• • Not be metastatic
• • OM grade 1 (according to NCI-CTCAE v4.03)
• • Be 18 years or older
• • Volunteer to participate in the study
• • Speak Turkish
• Exclusion Criteria:
• • Have an autoimmune disease
• • Have dental disease
• • Using dentures
• • Being allergic to thyme honey
• • Refusing to participate in the research
• • To have received radiotherapy treatment in the 6-month period before the start of the study
• • Criteria for terminating the study
• • The patient's desire to leave the study
• • Continuing the treatment in another city
• • Interruption or termination of radiotherapy treatment
• • Patient's death

Trial Officials