Study of Phantom Limb Pain Using Peripheral Nerve and Spinal Cord Stimulation

Launched by ARTUR BIKTIMIROV · Dec 6, 2022

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ClinConnect Summary

The purpose of this study is to evaluate the effectiveness of neuromodulation for relief of phantom limb pain (PLP) using peripheral nerve (PNS) and spinal cord stimulation (SCS) with implantable electrodes.

The study is conducted to collect information on the role of non-adaptive neuroplasticity and inhibitory descending antinociceptive influences, which determine the effect of peripheral nerve and spinal cord stimulation with implanted electrodes in patients with phantom limb pain as a result of amputation of the upper limb. Neuromodulation is a potential treatment option for chronic pai...

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Eligibility criteria

• Inclusion Criteria:
• • Patients with implanted neuromodulation devices.
• • Amputation of the upper limb at the level of the forearm.
• • Age ranges from 18 to 65 years old.
• • The duration from the moment of amputation is from 6 months.
• • The presence of persistent chronic pain syndrome is from 4 to 10 points according to the Visual Analogue Scale
• • Absence of pregnancy at the time of implantation, confirmed by a pregnancy test.
• Exclusion Criteria:
• • The presence of severe somatic pathology
• • The presence of mental illness
• • The presence of a gross orthopedic deformity in the limb above the amputation level.
• • The presence of oncology.
• • The presence of epilepsy.
• • Complications after a traumatic brain injury or stroke.
• • Purulent - septic pathology.
• • Drug addiction.
• • Congenital malformation of the upper limb.
• • Any conditions that, according to the researcher, fall under the exclusion criteria.