Comparison in Frequency of Hypotension Between Remimazolam and Propofol in Hip Surgery

Launched by ASAN MEDICAL CENTER · Dec 13, 2022

Keywords

ClinConnect Summary

This clinical trial is looking at how often patients experience low blood pressure, also known as hypotension, when receiving two different sedation medications—remimazolam and propofol—during hip surgery that uses spinal anesthesia. The goal is to find out which medication causes fewer incidents of low blood pressure while patients are sedated for their procedures.

To participate in this study, patients should be between 18 and 75 years old and must be scheduled for hip joint surgery with spinal anesthesia. They should also be in good health overall, which is determined by their ASA physical status (a system that measures a patient's fitness for surgery). However, those with certain medical conditions, allergies to the medications being tested, or specific health issues related to spinal anesthesia cannot join the trial. Participants will have the opportunity to help researchers understand how these medications work in real surgical settings, and their safety and effectiveness will be closely monitored throughout the study.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • ASA physical status 1-3
• • Patients scheduled for hip joint surgery under spinal anesthesia and sedation with propofol or remimzolam
• Exclusion Criteria:
• • Patients who refuse to participate in this study
• • Patients with uncontrolled high blood pressure, hyperthyroidism, dementia in the inability to communicate, or symptomatic coronary artery disease
• • Patients with an allergy to propofol, fentanyl, or bupivacaine
• • Patients contraindicated for spinal anesthesia, such as coagulopathy, severe aortic stenosis/mitral stenosis, and active infection on lumbar region
• • Patients judged to be inappropriate for this study