Trials
Search / Trial NCT05652426

The Effect of Hypoxic and Normoxic Cerebral Oximetry Levels on Cognitive Functions After Carotid Endarterectomy

Launched by DUZCE UNIVERSITY · Dec 7, 2022

Trial Information

Current as of January 21, 2025

Completed

Keywords

ClinConnect Summary

In this retrospective study, patients who were scheduled for carotid endarterectomy, examined the MOCA (Montreal cognitive assesment )tests before and after the operation and collected blood samples intraoperatively were included between January 2020-2021. The time periods specified below, blood samples were taken and serums were frozen at -80 celcius all this patients. Montreal cognitive function assessment test was applied before the operation, 24 hours and 7 days after the operation. Ten mililiters venous blood samples were collected to examine the status of basal neuron specific enolase...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients who were scheduled for carotid endarterectomy, examined the MOCA (Montreal cognitive assesment )tests before and after the operation and collected blood samples intraoperatively were included between January 2020-2021.
  • Exclusion Criteria:
  • Irregular diabetes mellitus
  • Pregnancy
  • Acute or chronic renal failure
  • Liver failure
  • History of previous carotid or brain trauma
  • Vasculitis
  • Thyroid diseases
  • Adrenal insufficiency
  • Patients who cannot perform cognitive function tests
  • Anemia (below 10 g/dl)
  • History of previous stroke in the last 6 months
  • Patients with plegia in the dominant upper extremity
  • Patients who will be shunted during the operation.
  • Patients with vertebrobacillary arterial system or ring of Willis anomaly
  • Presence of acute myocardial infarction.
  • Traumatic brain injuries less than 6 months before the study.

Trial Officials

İlknur S Yorulmaz

Principal Investigator

Duzce University

About Duzce University

Düzce University is a prominent academic institution located in Turkey, dedicated to advancing medical research and innovation. As a clinical trial sponsor, Düzce University leverages its extensive expertise in various fields of health sciences to conduct rigorous clinical studies aimed at improving patient outcomes and enhancing therapeutic strategies. The university fosters collaboration among multidisciplinary teams and prioritizes ethical standards and regulatory compliance in its research endeavors. Through its commitment to scientific excellence and community health, Düzce University plays a pivotal role in contributing to the global body of medical knowledge.

Locations

Düzce, , Turkey

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

Similar Trials