The Effect of Hypoxic and Normoxic Cerebral Oximetry Levels on Cognitive Functions After Carotid Endarterectomy
Launched by DUZCE UNIVERSITY · Dec 7, 2022
Trial Information
Current as of February 05, 2025
Completed
Keywords
ClinConnect Summary
In this retrospective study, patients who were scheduled for carotid endarterectomy, examined the MOCA (Montreal cognitive assesment )tests before and after the operation and collected blood samples intraoperatively were included between January 2020-2021. The time periods specified below, blood samples were taken and serums were frozen at -80 celcius all this patients. Montreal cognitive function assessment test was applied before the operation, 24 hours and 7 days after the operation. Ten mililiters venous blood samples were collected to examine the status of basal neuron specific enolase...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients who were scheduled for carotid endarterectomy, examined the MOCA (Montreal cognitive assesment )tests before and after the operation and collected blood samples intraoperatively were included between January 2020-2021.
- Exclusion Criteria:
- • Irregular diabetes mellitus
- • Pregnancy
- • Acute or chronic renal failure
- • Liver failure
- • History of previous carotid or brain trauma
- • Vasculitis
- • Thyroid diseases
- • Adrenal insufficiency
- • Patients who cannot perform cognitive function tests
- • Anemia (below 10 g/dl)
- • History of previous stroke in the last 6 months
- • Patients with plegia in the dominant upper extremity
- • Patients who will be shunted during the operation.
- • Patients with vertebrobacillary arterial system or ring of Willis anomaly
- • Presence of acute myocardial infarction.
- • Traumatic brain injuries less than 6 months before the study.
Trial Officials
İlknur S Yorulmaz
Principal Investigator
Duzce University
About Duzce University
Düzce University is a prominent academic institution located in Turkey, dedicated to advancing medical research and innovation. As a clinical trial sponsor, Düzce University leverages its extensive expertise in various fields of health sciences to conduct rigorous clinical studies aimed at improving patient outcomes and enhancing therapeutic strategies. The university fosters collaboration among multidisciplinary teams and prioritizes ethical standards and regulatory compliance in its research endeavors. Through its commitment to scientific excellence and community health, Düzce University plays a pivotal role in contributing to the global body of medical knowledge.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Düzce, , Turkey
People applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Discussion 0
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