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Search / Trial NCT05652647

A Study to Understand How the Study Medicine (PF-07081532) is Processed and Eliminated in Healthy Men

Launched by PFIZER · Dec 7, 2022

Trial Information

Current as of January 13, 2025

Completed

Keywords

Absorption Distribution Metabolism Elimination Bioavailability Fraction Absorbed Mass Balance Healthy Males

ClinConnect Summary

No description provided

Gender

MALE

Eligibility criteria

  • Key Eligibility criteria for this study include, but are not limited to the following:
  • Inclusion criteria:
  • Healthy Male participants must be 18 to 60 years of age, inclusive.
  • Overtly healthy as determined by medical evaluation including medical history, physical examination, blood pressure and pulse rate measurement, standard 12-lead ECG, and laboratory tests.
  • BMI of 17.5 to 30.5 kg/m2; and a total body weight \>50 kg (110 lb).
  • Participants who are willing and able to comply with all scheduled visits, treatment plan, laboratory tests, lifestyle considerations, and other study procedures
  • Exclusion criteria:
  • History of irregular bowel movements (eg, irritable bowel syndrome, frequent episodes of diarrhea, or constipation defined by less than 1 bowel movement on average per 2 days) or lactose intolerance
  • Any condition possibly affecting drug absorption (eg, gastrectomy, cholecystectomy).
  • Previous administration with an investigational product (drug or vaccine) within 90 days (or as determined by the local requirement) preceding the first dose of study intervention used in this study.
  • Total 14C radioactivity measured in plasma exceeding 11 mBq/mL.

Trial Officials

Pfizer CT.gov Call Center

Study Director

Pfizer

About Pfizer

Pfizer Inc. is a global leader in biopharmaceutical innovation, dedicated to discovering, developing, and delivering advanced therapies that enhance patient outcomes across a wide range of medical conditions. With a rich history of scientific research and a commitment to quality, Pfizer focuses on areas such as oncology, immunology, cardiology, and rare diseases. The company leverages cutting-edge technology and collaborates with healthcare professionals, regulatory bodies, and academic institutions to conduct rigorous clinical trials that ensure the safety and efficacy of its products. Pfizer's mission is to bring breakthroughs that change patients' lives, exemplifying its commitment to health and wellness worldwide.

Locations

Groningen, , Netherlands

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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