Does Joint Lavage Reduce Intraarticular Inflammation in High-energy Tibial Pilon Fractures?

Launched by UNITED STATES NAVAL MEDICAL CENTER, SAN DIEGO · Dec 7, 2022

Keywords

ClinConnect Summary

This clinical trial is investigating whether a procedure called joint lavage can help reduce inflammation in the ankle after a specific type of bone fracture known as a high-energy tibial pilon fracture. These fractures can lead to serious complications like post-traumatic arthritis, which causes joint pain and problems in movement. By cleaning out the joint and reducing inflammation, the researchers hope to improve short-term recovery for patients with this injury.

To participate in the trial, you need to be an adult (18 years or older) with a certain kind of unstable tibial pilon fracture that requires a specific type of temporary treatment. Unfortunately, individuals with certain conditions, such as open fractures, preexisting arthritis, or those who have had previous ankle surgeries, cannot take part. If you join, you can expect to receive the joint lavage treatment and be monitored for how it affects your recovery and inflammation levels. The trial is currently looking for volunteers, so if you think you might be eligible, it's a good idea to discuss it with your healthcare provider.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Male or female age 18 years or older
• • Present with an axially unstable tibial pilon fracture requiring temporary external fixation followed by delayed definitive internal fixation
• • Able to give informed consent
• Exclusion Criteria:
• • Open fractures
• • Delayed presentation greater than 72 hours post-injury
• • Associated talar body fracture
• • Presentation after initial ex-fix placement
• • Unreconstructable or unsalvageable joint
• • Preexisting ankle arthritis
• • Previous ankle surgery
• • Contralateral ankle injury
• • Age less than 18 years
• • Pregnant women
• • Individuals who are incarcerated