Effect of KETOgenic Diet on Metabolism, Inflammation, Nutrition Deficiencies and OXidative Stress in Women With Overweight

Launched by POLISH ACADEMY OF SCIENCES · Dec 7, 2022

Keywords

ClinConnect Summary

In recent times, the prevalence of obesity increases, reaching an epidemic scale. A new factor supporting a weight gain is a current coronaviros (COVID-19) pandemic, associated with reduced physical activity, high stress and overeating, which resulted in 2-5 kg weight gain in 20 % of the American population within a few months 1. Elevated body weight is a risk factor in developing several diseases such as diabetes, hypertension and cancer. Therefore, obesity management solutions, such as diet therapy, are needed. The critical issue is to choose the most appropriate diet to obtain an efficie...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • women
• • age 18-45
• • overweight (BMI 27 - 35)
• • motivation to lose weight and participate in the nutritional intervention trial
• Exclusion Criteria:
• • overweight/obesity secondary to genetic syndromes
• • endocrine diseases, acute systemic disease, autoimmune disorders
• • pregnancy
• • breastfeeding
• • type 1 and 2 diabetes
• • any other chronic diseases requiring pharmacotherapy (including topical steroids in allergy disorders
• • supplement or medication use influencing appetite, weight or metabolism)
• • participation in other clinical trials
• • severe obesity (BMI \> 35)
• • \> 3 kg weight loss 12 weeks before the initial test day
• • extreme changes in exercise intensity 4 weeks prior
• • any diagnosed psychiatric disorders

Trial Officials