The Use of Adhesion Molecule Loaded Hydrogel With Minimally Invasive Surgical Technique in Treatment of Periodontal Intrabony Defect

Launched by MINIA UNIVERSITY · Dec 7, 2022

Keywords

ClinConnect Summary

Periodontitis is a multifactorial inflammatory disease associated with dysbiotic plaque biofilms and characterized by clinical attachment loss caused by the destruction of the periodontal ligament and loss of supporting bone. One of periodontal therapy goals is regeneration of the lost periodontal attachment apparatus.

. To regenerate healthy periodontal tissue, various clinical techniques were developed to prevent downward epithelial migration and promote periodontal tissue regeneration by the remaining periodontal ligament (PDL) cells or osteoblasts such as open flap debridement (OFD), n...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • - Patients with diagnosis of periodontitis (stage III or IV and grade B or C) according to new American Academy of Periodontology classification (Tonetti et al., 2018a) (Nguyen et al., 2021).
• • Selected patients of both sexes were 20-55 years old.
• • All single and multiple rooted teeth in both maxilla and mandible.
• • Presence of interdental periodontal pocket with intrabony defect.
• • Patients were free from any systemic diseases that could alter their periodontal status, complicate the surgical treatment, or affect healing according to Modified Cornell Index (Abramson, 1966).
• • No antibiotics or any medications that affect bone or soft tissue condition were taken during the last six months.
• Exclusion Criteria:
• • Patients who received regenerative periodontal therapy last 6 months before the initial examination.
• • Pregnant or lactating females.
• • Smokers were not included as participants in this study.
• • Patients not committed to oral hygiene after the re-evaluation of phase I therapy.
• • Teeth with mobility more than Grade I.
• • Third molars.