Expression of IL-8 Before and After Root Canal Treatment in Patients With Symptomatic Apical Periodontitis
Launched by CAIRO UNIVERSITY · Dec 7, 2022
Trial Information
Current as of January 22, 2025
Completed
Keywords
ClinConnect Summary
Diagnosis:
* Personal data including name, address and phone number in addition to medical history and dental history will be collected from each patient in specific forms, then history of chief complaint will be recorded. The selected patients should show symptoms of symptomatic apical periodontitis (SAP) either associated with vital or necrotic teeth.
* Extra-oral and intra-oral clinical examination of the suspected tooth will be performed tentatively using a diagnostic mirror and probe.
* Radiograph will be taken using bisecting angle technique with a periapical digital sensor.
* The di...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Medically free patients
- • Single canaled teeth diagnosed clinically with symptomatic apical periodontitis.
- • Radiographic widening in the periodontal membrane space.
- • Presence of pain on percussion.
- • Patients' acceptance to participate in the trial.
- Exclusion Criteria:
- • Medically compromised patients.
- • Pregnant women: Avoid radiation exposure, anesthesia, and medication.
- • If analgesics or antibiotics have been administrated by the patient during the past 24 hours preoperatively.
- • Teeth that shows association with acute periapical abscess or swelling: Need special treatment steps which could involve additional visits with incision and drainage.
- • Presence of periodontal disease
- • Non restorability
- • Immature teeth
- • Radiographic evidence of external or internal root resorption vertical root fracture, perforation, calcification.
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Giza, , Egypt
People applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Discussion 0
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