Trials
Search / Trial NCT05653947

Expression of IL-8 Before and After Root Canal Treatment in Patients With Symptomatic Apical Periodontitis

Launched by CAIRO UNIVERSITY · Dec 7, 2022

Trial Information

Current as of January 22, 2025

Completed

Keywords

Interleukin 8 Apical Periodontitis

ClinConnect Summary

Diagnosis:

* Personal data including name, address and phone number in addition to medical history and dental history will be collected from each patient in specific forms, then history of chief complaint will be recorded. The selected patients should show symptoms of symptomatic apical periodontitis (SAP) either associated with vital or necrotic teeth.
* Extra-oral and intra-oral clinical examination of the suspected tooth will be performed tentatively using a diagnostic mirror and probe.
* Radiograph will be taken using bisecting angle technique with a periapical digital sensor.
* The di...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Medically free patients
  • Single canaled teeth diagnosed clinically with symptomatic apical periodontitis.
  • Radiographic widening in the periodontal membrane space.
  • Presence of pain on percussion.
  • Patients' acceptance to participate in the trial.
  • Exclusion Criteria:
  • Medically compromised patients.
  • Pregnant women: Avoid radiation exposure, anesthesia, and medication.
  • If analgesics or antibiotics have been administrated by the patient during the past 24 hours preoperatively.
  • Teeth that shows association with acute periapical abscess or swelling: Need special treatment steps which could involve additional visits with incision and drainage.
  • Presence of periodontal disease
  • Non restorability
  • Immature teeth
  • Radiographic evidence of external or internal root resorption vertical root fracture, perforation, calcification.

About Cairo University

Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.

Locations

Giza, , Egypt

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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