Distal Radius Steroid

Launched by INDIANA HAND TO SHOULDER CENTER · Dec 14, 2022

Keywords

ClinConnect Summary

This will be a prospective, randomized, partially blinded, controlled trial where patients are randomized in a centralized fashion into 2 groups: a) Control group with no intraoperative glucocorticoids administered or b) Test group with administration of 10 mg glucocorticoids intraoperatively followed with a 6-day oral methylprednisolone taper course prescribed as a Medrol Dose Pack. Each group will enroll 30 patients for a study total of 60 over approximately a one year enrollment period. Randomization will be set up using sealedenvelope.com simple randomizer. The randomization process wil...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Intra- or extra-articular distal radius fractures (AO 23-A2,3; 23B-1,2,3; 23C-1,2,3) treated with open reduction internal fixation (ORIF)
• • Age \>18
• Exclusion Criteria:
• • Open fractures
• • Pathologic fractures
• • Concomitant ipsilateral upper extremity fracture (not including distal ulna)
• • Medical contraindication to systemic glucocorticoids (insulin-dependent Diabetes mellitus, history of avascular necrosis, allergy)
• • Narcotic dependence
• • Women who are pregnant or breastfeeding