Clinical and Biochemical Assessment of Ozonated Olive Oil Mixed Bone Substitute in Treating Intra Bony Periodontal Defect

Launched by AIN SHAMS UNIVERSITY · Dec 10, 2022

Keywords

ClinConnect Summary

This clinical trial is studying a new treatment for gum disease known as periodontitis, specifically looking at how ozonated olive oil can help heal bone defects in the jaw caused by this condition. Researchers want to see if this treatment can improve both clinical signs (like gum health) and radiographic results (like X-ray images of the bone). To participate, individuals need to have chronic periodontitis that requires surgery to fix a specific type of bone defect near a natural tooth. Eligible participants should be generally healthy and available for multiple follow-up visits.

If you join the study, you will receive the ozonated olive oil treatment and have regular check-ups to monitor your progress. This trial is open to all genders and participants aged between 18 and 65, but certain health conditions, like pregnancy or smoking, may prevent involvement. Your safety is important, so the study will also exclude anyone with untreated infections or other serious dental issues. Overall, this research aims to find a potentially beneficial new approach for treating periodontitis and improving patients' oral health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • chronic periodontitis requiring surgical intervention to treat an intra-bony defect adjacent to a natural tooth One or more periodontal defects with PD \>6 mm, radiographic vertical bony defect \>3 mm in depth, and radiographic base of defect \>2 mm coronal to the root apex.
• • Systemically healthy as evidence by a medical questionnaire guided by modified cornel medical index Availability for multiple follow-up appointments.
• Exclusion Criteria:
• • Smokers women who were pregnant or intended to become pregnant during the study period Patient unwilling to perform hygienic instructions Untreated infection at the study site other than periodontitis Tooth mobility Miller Class II or III Subgingival restoration, untreated caries at or below the cement enamel junction (CEJ), root fracture, or apical pathology.
• • Vulnerable individuals Presence of systemic diseases.
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