VGH-DESJS-1 in Ocular and Oral Dryness Symptoms of Dry Eye Syndrome and Sjögren's Syndrome

Launched by TAIPEI VETERANS GENERAL HOSPITAL, TAIWAN · Dec 11, 2022

Keywords

ClinConnect Summary

Method: This study wants to evaluate the Chinese herbal tea VGH-DESJS-1 on Nourishing Yin and Moistening Dryness the ocular dryness from dry eye syndrome (DES) and Sjögren's syndrome (SJS). One hundred dry eye subjects are composed of 30 dry eye syndrome subjects, 60 Sjögren's syndrome' dry eye subjects, and 10 non DES SJS Healthy Controls, NHC). DES, SJS, and NHC received VGH-DESJS-1 daily during 8 weeks for the evaluation before and after the subjects receiving the VGH-DESJS-1. Moreover, we could use the Whole-genome genotyping, Schirmer's test, Tear breakup time (TBUT), Cytokines, Ocular...

Gender

ALL

Eligibility criteria

• • Dry eye syndrome
• • -Inclusion Criteria: aged between 20 and 75 years Schirmer's test less than 10 mm/5 min
• • -Exclusion Criteria: Pregnancy With eye inflammation or infectious eye disease Accepted operation of eye
• • Sjögren's syndrome
• • -Inclusion Criteria: primary or secondary SS aged between 20 and 75 years fulfilled the 2002 American-European Consensus Criteria for SS (AECG) had no abnormal findings of immune, liver, kidney, or blood function evaluations.
• • -Exclusion Criteria: a history of alcohol abuse, diabetes mellitus, or major life-threatening condition pregnancy or breastfeeding steroid pulse therapy within three months prior to the commencement of our study.
• • non AIDDES Healthy Controls
• • -Inclusion Criteria: aged between 20 and 75 years without any Chronic disease
• • -Exclusion Criteria: any Sjögren's syndrome or Dry eye syndrome.

Trial Officials