A Repository to Study Host-Microbiome Interactions in Health and Disease

Launched by NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES (NIAID) · Dec 16, 2022

Keywords

ClinConnect Summary

This clinical trial is focused on studying the microbiome, which refers to the tiny bacteria and microorganisms that live in and on our bodies. Researchers believe that the microbiome plays a crucial role in our health and in how our bodies respond to illnesses. To better understand these interactions, the study aims to collect samples from the microbiomes of different groups of people, including healthy individuals, pregnant women, and children with certain illnesses. These samples will be stored for future research to help us learn more about how the microbiome impacts our health.

If you or someone you know is interested in participating, you need to be at least 3 years old and willing to provide biological samples like stool, saliva, or blood, among others. Participants will fill out a questionnaire about their health and diet, and most sample collections can be done at home with simple instructions. This study is currently recruiting participants of all ages and genders. It’s a great opportunity to contribute to important research that could improve our understanding of health and disease.

Gender

ALL

Eligibility criteria

• * INCLUSION CRITERIA:
• In order to be eligible to participate in this study, an individual must meet all of the following criteria:
• • Aged \>0 years. Only participants \>3 years old will be seen at the NIH CC.
• • Willing to allow biological samples and data to be stored for future research.
• • Willing to provide at least one of the requested biospecimens.
• EXCLUSION CRITERIA:
• • An individual who has any condition that, in the judgment of the investigator, may put them at undue risk or make them unsuitable for participation in the study will be excluded.
• • For additional gastrointestinal and skin biopsies only, individuals on blood thinners unless they have already been stopped for the procedure.
• • For additional gastrointestinal biopsies only, individuals who have a history of gastrointestinal perforation with endoscopic biopsies will be excluded from the collection of additional gastrointestinal biopsies for the repository.
• • For additional gastrointestinal biopsies only, healthy children (\<18 years old).
• • For skin biopsies only, individuals who have a history of keloid formation.
• • For vaginal swabs and vaginal fluid only, individuals who have not started menses.
• • For breast milk only, non-lactating individuals.

Trial Officials