EEG DSA-guided Intravenous Anesthesia Using Dexmedetomidine and Propofol

Launched by NATIONAL TAIWAN UNIVERSITY HOSPITAL · Dec 11, 2022

Keywords

ClinConnect Summary

This clinical trial is studying a new way to give anesthesia during brain surgery. Researchers want to see if using a special technique called EEG spectrogram can help doctors give less of a medication called propofol, when it's combined with another drug called dexmedetomidine. The goal is to improve the safety and outcomes for patients undergoing procedures like brain tumor removal or aneurysm clipping.

To participate in this study, patients must be between 20 and 80 years old and scheduled for specific types of brain surgery. However, individuals with certain health issues, such as severe liver or kidney problems, or heart failure, may not be eligible. If chosen to participate, patients can expect close monitoring during their surgery to see how this method impacts their recovery and overall experience.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients undergoing elective craniotomy for brain tumor resection, aneurysm clipping, an intracranial bypass procedure, or microvascular decompression
• • age between 20 to 80 yr
• Exclusion Criteria:
• • Fever, elevated white blood cell or C-reactive protein
• • Impaired liver function, eg. AST or ALT \>100; liver cirrhosis \> Child B class
• • Impaired renal function, cGFR\< 60 ml/min/1.73 m2
• • Cardiac dysfunction, such as heart failure \> NYHA class II

Trial Officials