Peritoneal Lavage on the Incidence of Pancreatic Fistula and Related Complications After Pancreatoduodenectomy

Launched by SECOND AFFILIATED HOSPITAL, SCHOOL OF MEDICINE, ZHEJIANG UNIVERSITY · Dec 18, 2022

Keywords

ClinConnect Summary

This clinical trial is exploring whether a procedure called peritoneal lavage, which involves flushing the abdominal cavity with fluid after surgery, can help prevent complications like pancreatic fistulas after a type of surgery called pancreatoduodenectomy. A pancreatic fistula is a leak that can occur when the pancreas is operated on, and it can lead to serious health issues. The researchers want to compare this flushing method to simply allowing the body to drain naturally to see which approach is better at reducing these complications.

To participate in this trial, patients should be diagnosed with certain types of tumors in the pancreas or nearby areas and be eligible for surgery. They must also be able to understand and agree to the study. However, patients with serious health problems in other organs, those who may have to change their surgery unexpectedly, or those who cannot follow the study plan will not be included. If you join the study, you can expect to receive care that is closely monitored to help assess the effectiveness of the two different approaches.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Preoperative diagnosis was pancreatic head, lower common bile duct, ampulla and duodenum tumors;
• • 2. Patients with resectable tumors evaluated by imaging examination, and patients who plan to undergo pancreatoduodenectomy;
• • 3. Subjects informed consent, understood and were willing to cooperate with the trial protocol, and signed relevant documents.
• Exclusion Criteria:
• • 1. Complicated with severe liver, kidney, heart, brain, lung and other organ complications;
• • 2. Intraoperative changes in surgical methods, such as patients with tumor dissemination and only abdominal opening and closing; Or it needs to be resected in combination with other organs;
• • 3. Patients and their families do not understand the treatment implementation plan of this study;
• • 4. Failure to complete follow-up;