Pain Relief Effect of Low-intensity Continuous Ultrasound Stimulator for Knee Arthritis

Launched by KYU JAE LEE · Dec 15, 2022

Keywords

ClinConnect Summary

Subject: 35 osteoarthritis patients Evaluation measure: Visual Analogue Scale (VAS), McMaster Universities Osteoarthritis Index (WOMAC) Method: A total of 35 subjects were selected in consideration of the dropout rate of 20%. Selected subjects were treated as a single group without randomization, and an appropriate amount of gel was applied to the knee OA pain area for 4 weeks. A blinded evaluation at baseline and after treat-ment was made. Primary outcome was pain on movement assessed by the VAS index. Secondary outcomes consisted of the WOMAC scores.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients aged 40 to 60 years with pain due to OA of the knee and able to walk voluntarily
• • Those who have more than one osteophyte in the tibiofemoral joint on radiographic findings (Kellgren-Lawrence gradesⅡ,Ⅲ)
• • At visit 1 (screening) and visit 2, the pain status during knee OA activity was 100 mm pain VAS, as a result, those who are over 40mm
• • If the Kellgren \& Lawrence Grades are the same, target the one with the higher 100mm pain VAS
• • Patients who are willing or able to follow the doctor's instructions, including joint movements
• • Persons who can comply with concomitantly permitted drugs, prohibited drugs, and relief drugs
• • Persons who can maintain the same exercise and activity during the clinical trial period
• • Fully understand the purpose and procedure of this clinical trial
• Exclusion Criteria:
• • Those who have a history of rheumatoid arthritis or gouty arthritis or who have peripheral pain other than the knee joint patient.
• • Those with fractures or dislocations on simple radiological examination.
• • Those who are identified, or those with a similar risk of neuromuscular disease
• • Those who have participated in other clinical trials within 6 months of participating in clinical trials.
• • Patients with severe pain in the knee joint other than angular deformity, instability, and index knee in the knee joint
• • Patients with other tumors other than degenerative knee arthrosis
• • Persons with systemic symptoms that may affect knee pain
• • Pregnant and lactating women

Trial Officials