Preoperative Supine Time for Adrenal Venous Sampling

Launched by SECOND AFFILIATED HOSPITAL, SCHOOL OF MEDICINE, ZHEJIANG UNIVERSITY · Dec 13, 2022

Keywords

ClinConnect Summary

This clinical trial is investigating how the time patients spend lying down before a specific test called adrenal venous sampling (AVS) might affect the results. The study focuses on individuals diagnosed with primary aldosteronism, a condition that can cause high blood pressure and other health issues. Researchers want to see if adjusting the time a patient lies flat before the test can improve the chances of getting accurate results.

To participate in this trial, patients need to be at least 18 years old and have a confirmed diagnosis of primary aldosteronism based on specific hormone levels. Some individuals may not be eligible, such as those with certain types of adrenal tumors or those who have had recent treatments affecting hormone levels. Participants will undergo the AVS procedure, and the trial is currently recruiting volunteers of all genders. If you're considering joining, it’s an opportunity to contribute to important research that could help improve testing for this condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients are clinically diagnosed as primary aldosteronism with ARR≥37 (PAC showed as pg/ml, renin showed as μIU/mL) and passed through PA confirmatory tests (PAC-post CCT\>110pg/ml, PAC-post SSIT \>80pg/ml, or PAC-post FST\>60pg/ml). PAC: plasma aldosterone concentration;
• • 2. Patients with willing for AVS;
• • 3. Age 18 or above, male or female, with legal capacity.
• Exclusion Criteria:
• • 1. Patients with suspected adrenocortical carcinoma or pheochromocytoma;
• • 2. Patients with high risk of adrenal surgery;
• • 3. Patients have been subtyping to glucocorticoid-suppressible hyperaldosteronism or familial hyperaldosteronism type III;
• • 4. Patients were diagnosed as Cushing syndrome or subclinical Cushing syndrome;
• • 5. Patients were treated with glucocorticoids recently;
• • 6. Patients with whole body or venipuncture area infection;
• • 7. Patients with venous access thrombosis;
• • 8. Patients are allergic to iodine;
• • 9. Patients with X-ray contraindications;
• • 10. Patients with coagulation dysfunction;
• • 11. Patients are unable to cooperate and follow-up.

Trial Officials