RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty

Launched by UNIVERSITY OF PITTSBURGH · Dec 16, 2022

Keywords

ClinConnect Summary

The RXWell trial is studying how to help patients manage their mood and anxiety before and after knee surgery, specifically total knee arthroplasty (TKA). The goal is to see if using the RxWell platform can help improve recovery, reduce the need for pain medication like opioids, and enhance overall patient care. This study is currently active but not recruiting new participants.

To be eligible for this trial, participants need to be adults over 18 years old who are scheduled for elective knee surgery and have moderate levels of anxiety or depression as measured by specific questionnaires. However, individuals with severe mental health issues or those who cannot access a smartphone or tablet will not be able to participate. If you join the trial, you can expect to receive support for managing your mood during the surgery process, which may help you recover faster and use fewer resources. This approach aims to provide a more holistic way of taking care of patients’ emotional and physical health throughout their surgical journey.

Gender

ALL

Eligibility criteria

• Inclusion Criteria for the RXWell Study:
• • Adults \>18 years
• • Scheduled for elective primary total knee arthroplasty (TKA) or hip replacement (THA) at the approved UPMC hospitals
• • Moderately high levels of mood disorder symptoms on validated PROMIS measures, defined as a T-score \> or = to 60 on PROMIS Anxiety 4a short form and/or PROMIS Depression4a short form
• Exclusion Criteria for the RXWell Study:
• • Patients undergoing non-elective surgery or secondary arthroplasty
• • Active delirium, neurocognitive impairment, or severe intellectual disability
• • No access to a smart device (phone or tablet)
• • Active alcoholism (defined as daily use of more than 1 liter of wine and /or 3 or more shots of hard liquor) or drug abuse (defined as daily use of illicit drugs)
• • Profound mood disorders requiring immediate intervention such as suicidal ideation, defined as a PROMIS Depression score of more than 70
• • A PROMIS Anxiety and/or Depression T-score \>70, which corresponds to severe anxiety and depression.
• • Patients needing immediate care will be referred to psychiatrists and primary team.