Physiology Optimized Versus Angio-guided PCI
Launched by UNIVERSITY HOSPITAL OF FERRARA · Dec 10, 2022
Trial Information
Current as of January 22, 2025
Completed
Keywords
ClinConnect Summary
Despite the accumulating evidence regarding functional indices utility in setting the indication to and planning percutaneous coronary interventions (PCI), the use of functional assessment in clinical practice is still limited. This is especially true in the post-PCI setting, probably due to lack of evidence and/or specific guidelines/recommendations on how to "react" to a suboptimal post-PCI functional result.
New indices and tools have been developed in an effort to overcome the barriers to a widespread adoption of functional assessment.
All these technological advances brought physiolo...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Indication to PCI for either acute or chronic coronary syndrome
- • 2. Signed informed consent
- 3. At least one of the following CHIP lesion characteristic:
- • Long lesion (\>28 mm);
- • Tandem lesions;
- • Severe calcifications;
- • Severe tortuosity;
- • True bifurcation lesions: involving a significant (\> 50%) diameter stenosis both in the main vessel and side branch (i.e. MEDINA 1,1,1; 1,0,1; or 0,1,1) and with a relevant side branch, namely ≥2.00 mm;
- • In-stent restenosis (ISR).
- • Left main stem disease.
- Exclusion Criteria:
- • 1. Planned surgical revascularization
- • 2. Prior Coronary Artery Bypass Graft (CABG) Surgery
- • 3. Culprit lesion of STEMI or NSTEMI
- • 4. Revascularization of a chronic total occlusion
- • 5. Non-cardiovascular co-morbidity reducing life expectancy to \< 1 year
- • 6. Any factor precluding 1-year follow-up
About University Hospital Of Ferrara
The University Hospital of Ferrara, a leading academic medical institution in Italy, is dedicated to advancing healthcare through innovative research and clinical excellence. Affiliated with the University of Ferrara, the hospital is known for its commitment to integrating cutting-edge scientific inquiry with patient care. With a multidisciplinary approach, the institution conducts a wide range of clinical trials aimed at enhancing treatment methodologies and improving patient outcomes in various medical fields. The University Hospital of Ferrara prioritizes ethical standards and patient safety, fostering a collaborative environment that engages researchers, healthcare professionals, and patients in the pursuit of medical advancement.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cona, Ferrara, Italy
Latina, Lt, Italy
People applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Discussion 0
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