Trials
Search / Trial NCT05658952

Physiology Optimized Versus Angio-guided PCI

Launched by UNIVERSITY HOSPITAL OF FERRARA · Dec 10, 2022

Trial Information

Current as of February 05, 2025

Completed

Keywords

Percutaneous Coronary Intervention Fractional Flow Reserve Virtual Pci Plan

ClinConnect Summary

Despite the accumulating evidence regarding functional indices utility in setting the indication to and planning percutaneous coronary interventions (PCI), the use of functional assessment in clinical practice is still limited. This is especially true in the post-PCI setting, probably due to lack of evidence and/or specific guidelines/recommendations on how to "react" to a suboptimal post-PCI functional result.

New indices and tools have been developed in an effort to overcome the barriers to a widespread adoption of functional assessment.

All these technological advances brought physiolo...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Indication to PCI for either acute or chronic coronary syndrome
  • 2. Signed informed consent
  • 3. At least one of the following CHIP lesion characteristic:
  • Long lesion (\>28 mm);
  • Tandem lesions;
  • Severe calcifications;
  • Severe tortuosity;
  • True bifurcation lesions: involving a significant (\> 50%) diameter stenosis both in the main vessel and side branch (i.e. MEDINA 1,1,1; 1,0,1; or 0,1,1) and with a relevant side branch, namely ≥2.00 mm;
  • In-stent restenosis (ISR).
  • Left main stem disease.
  • Exclusion Criteria:
  • 1. Planned surgical revascularization
  • 2. Prior Coronary Artery Bypass Graft (CABG) Surgery
  • 3. Culprit lesion of STEMI or NSTEMI
  • 4. Revascularization of a chronic total occlusion
  • 5. Non-cardiovascular co-morbidity reducing life expectancy to \< 1 year
  • 6. Any factor precluding 1-year follow-up

About University Hospital Of Ferrara

The University Hospital of Ferrara, a leading academic medical institution in Italy, is dedicated to advancing healthcare through innovative research and clinical excellence. Affiliated with the University of Ferrara, the hospital is known for its commitment to integrating cutting-edge scientific inquiry with patient care. With a multidisciplinary approach, the institution conducts a wide range of clinical trials aimed at enhancing treatment methodologies and improving patient outcomes in various medical fields. The University Hospital of Ferrara prioritizes ethical standards and patient safety, fostering a collaborative environment that engages researchers, healthcare professionals, and patients in the pursuit of medical advancement.

Locations

Cona, Ferrara, Italy

Latina, Lt, Italy

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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