Physiology Optimized Versus Angio-guided PCI

Launched by UNIVERSITY HOSPITAL OF FERRARA · Dec 10, 2022

Keywords

ClinConnect Summary

Despite the accumulating evidence regarding functional indices utility in setting the indication to and planning percutaneous coronary interventions (PCI), the use of functional assessment in clinical practice is still limited. This is especially true in the post-PCI setting, probably due to lack of evidence and/or specific guidelines/recommendations on how to "react" to a suboptimal post-PCI functional result.

New indices and tools have been developed in an effort to overcome the barriers to a widespread adoption of functional assessment.

All these technological advances brought physiolo...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Indication to PCI for either acute or chronic coronary syndrome
• • 2. Signed informed consent
• 3. At least one of the following CHIP lesion characteristic:
• • Long lesion (\>28 mm);
• • Tandem lesions;
• • Severe calcifications;
• • Severe tortuosity;
• • True bifurcation lesions: involving a significant (\> 50%) diameter stenosis both in the main vessel and side branch (i.e. MEDINA 1,1,1; 1,0,1; or 0,1,1) and with a relevant side branch, namely ≥2.00 mm;
• • In-stent restenosis (ISR).
• • Left main stem disease.
• Exclusion Criteria:
• • 1. Planned surgical revascularization
• • 2. Prior Coronary Artery Bypass Graft (CABG) Surgery
• • 3. Culprit lesion of STEMI or NSTEMI
• • 4. Revascularization of a chronic total occlusion
• • 5. Non-cardiovascular co-morbidity reducing life expectancy to \< 1 year
• • 6. Any factor precluding 1-year follow-up