Block Pressor Response to Intubation

Launched by ASSIUT UNIVERSITY · Dec 18, 2022

Keywords

ClinConnect Summary

Fast-track laparoscopic gynecological surgery usually done under general anesthesia (GA). Laryngoscopy and endotracheal intubation are necessary for effective control of airway and ventilation, but it has deleterious effects such as hypertension and disrhythmia. These hemodynamic changes are due to the reflex sympathetic activity and the magnitude of response is directly proportional to the duration and strength of laryngoscopy. Several drugs and techniques have been tried to attenuate the stress response to laryngoscopy and endotracheal intubation, but none of them have proven to be ideal....

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • ASA physical status I-II
• • Age between 23 to 40 years
• • With airway of Mallampati grade I and II
• • Elective diagnostic laparoscopic gynecologic surgery under general anesthesia with endotracheal intubation
• Exclusion Criteria:
• • Mallampatti grading III and IV, anticipated difficult intubation
• • Body mass index (BMI \> 35 kg/m2), full stomach, pregnancy
• • Emergency surgery
• • History of cardiac or neurological disease or patient with asthma
• • History of Hypersensitivity to the study drugs
• • Advanced hepatic or renal failure.
• • Patients in whom the duration of laryngoscopy lasted more than 20 seconds
• • Patient refusal.