Trials
Search / Trial NCT05659888

Real Life Lipid Management in Hospitals Not Participating in PENELOPE Trial - Control Population for PENELOPE

Launched by CLINICAL OPERATIONS WCN B.V. · Dec 12, 2022

Trial Information

Current as of February 05, 2025

Completed

Keywords

ClinConnect Summary

The recent PENELOPE study was designed to determine the effect of a protocolized, Dutch-, and ESC- guideline based strategy of stepwise intensified lipid management in patients at very high risk for ACS. In PENELOPE 22 Dutch non-academic hospitals, members of the WCN investigator network, implemented a protocol guided guideline approach in a consecutive cohort of very high-risk patients admitted for ACS over the period 01-01-2019 to 31-08-2020. Lipid values and medication strategy are collected at baseline (index ACS), and after three months and one year post ACS, in order to establish the ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age \>18 and ≤70 years
  • Alive at hospital discharge after admission for (N)STEMI between 1-1-2019 and 31-08-2020
  • Planned for follow-up at a participating PENELOPE CTRL site
  • * History of T2DM and/or history of ASCVD defined as either one of:
  • cerebrovascular disease/ event: transient ischemic attack, cerebral infarction, amaurosis fugax, retinal infarction
  • Coronary artery disease/ event: unstable angina pectoris, MI, ACS, coronary revascularization (coronary angioplasty or surgical procedure for coronary bypass)
  • Peripheral artery disease (symptomatic and documented obstruction of a distal extremity artery or surgical intervention (percutaneous transluminal angioplasty, bypass or amputation)
  • Exclusion Criteria:
  • Pregnant and lactating women
  • Participation in lipid modifying drug trials up to two years after index cardiovascular event

Trial Officials

Marco Alings

Principal Investigator

WCN

About Clinical Operations Wcn B.V.

Clinical Operations WCN B.V. is a dedicated clinical trial sponsor specializing in the management and execution of clinical research across various therapeutic areas. With a commitment to advancing medical knowledge and improving patient outcomes, WCN B.V. employs a team of experienced professionals who leverage innovative methodologies and robust operational frameworks to ensure the successful execution of clinical studies. The organization is focused on fostering collaboration with research institutions and healthcare providers, aiming to streamline processes and enhance the efficiency of clinical trials while adhering to the highest regulatory standards.

Locations

Veldhoven, , Netherlands

Delft, , Netherlands

Den Haag, , Netherlands

Utrecht, , Netherlands

Deventer, , Netherlands

Helmond, , Netherlands

Leiden, , Netherlands

Den Haag, , Netherlands

Emmen, , Netherlands

Alkmaar, , Netherlands

Hardenberg, , Netherlands

Meppel, , Netherlands

Nijmegen, , Netherlands

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

Similar Trials