Electrical Impedance Tomography & Selective Stimulation of Vagus Nerve
Launched by UNIVERSITY COLLEGE, LONDON · Dec 15, 2022
Trial Information
Current as of July 09, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a new way to help treat conditions like epilepsy and other diseases related to the vagus nerve, which is a major nerve that connects the brain to many organs in the body. Researchers want to understand how this nerve works and how they can safely stimulate it using electrical methods. They will use a special imaging technique called Electrical Impedance Tomography (EIT) to create detailed images of the vagus nerve and see how it interacts with different organs like the heart and lungs. The goal is to find a targeted way to stimulate the vagus nerve, which could lead to better treatments with fewer side effects.
To participate in the trial, you need to be over 18 years old and have a medical condition that could benefit from vagus nerve stimulation. If you decide to join, you will take part in a procedure where researchers will use a non-invasive device to stimulate your vagus nerve and capture images to better understand its function. It’s important to note that this study may not be suitable for everyone, especially if you cannot communicate in English or understand the information being provided. This trial is currently recruiting participants, so if you’re interested, you can discuss it with your healthcare provider.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age over 18
- • Written informed consent by patient or proxy
- • Clinical diagnosis of disorder affected directly or indirectly or will possibly respond to vagus nerve stimulation
- Exclusion Criteria:
- • Aged 17 and below
- • Unfortunately, it is unlikely that interpreters of all languages will be available in the unit so persons who cannot understand verbal explanation in English and for whom we could not find a suitable consultee would have to be excluded from the study.
About University College, London
University College London (UCL) is a leading global research institution renowned for its commitment to advancing healthcare through innovative clinical trials. As a prominent sponsor of clinical research, UCL leverages its multidisciplinary expertise and state-of-the-art facilities to conduct rigorous investigations aimed at improving patient outcomes and addressing pressing medical challenges. The institution fosters collaboration among researchers, healthcare professionals, and industry partners, ensuring that its trials adhere to the highest ethical standards and regulatory guidelines. UCL's dedication to translating scientific discoveries into practical applications underscores its role as a vital contributor to the advancement of medical science and public health.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
London, Greater London, United Kingdom
Patients applied
Trial Officials
Kirill Aristovich
Principal Investigator
University College, London
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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