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Search / Trial NCT05664854

Electrical Impedance Tomography & Selective Stimulation of Vagus Nerve

Launched by UNIVERSITY COLLEGE, LONDON · Dec 15, 2022

Trial Information

Current as of July 09, 2025

Recruiting

Keywords

Electrical Impedance Tomography Selective Vagus Nerve Stimulation Vagus Nerve Electrophysiology Vagus Nerve Stimulation

ClinConnect Summary

This clinical trial is studying a new way to help treat conditions like epilepsy and other diseases related to the vagus nerve, which is a major nerve that connects the brain to many organs in the body. Researchers want to understand how this nerve works and how they can safely stimulate it using electrical methods. They will use a special imaging technique called Electrical Impedance Tomography (EIT) to create detailed images of the vagus nerve and see how it interacts with different organs like the heart and lungs. The goal is to find a targeted way to stimulate the vagus nerve, which could lead to better treatments with fewer side effects.

To participate in the trial, you need to be over 18 years old and have a medical condition that could benefit from vagus nerve stimulation. If you decide to join, you will take part in a procedure where researchers will use a non-invasive device to stimulate your vagus nerve and capture images to better understand its function. It’s important to note that this study may not be suitable for everyone, especially if you cannot communicate in English or understand the information being provided. This trial is currently recruiting participants, so if you’re interested, you can discuss it with your healthcare provider.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age over 18
  • Written informed consent by patient or proxy
  • Clinical diagnosis of disorder affected directly or indirectly or will possibly respond to vagus nerve stimulation
  • Exclusion Criteria:
  • Aged 17 and below
  • Unfortunately, it is unlikely that interpreters of all languages will be available in the unit so persons who cannot understand verbal explanation in English and for whom we could not find a suitable consultee would have to be excluded from the study.

About University College, London

University College London (UCL) is a leading global research institution renowned for its commitment to advancing healthcare through innovative clinical trials. As a prominent sponsor of clinical research, UCL leverages its multidisciplinary expertise and state-of-the-art facilities to conduct rigorous investigations aimed at improving patient outcomes and addressing pressing medical challenges. The institution fosters collaboration among researchers, healthcare professionals, and industry partners, ensuring that its trials adhere to the highest ethical standards and regulatory guidelines. UCL's dedication to translating scientific discoveries into practical applications underscores its role as a vital contributor to the advancement of medical science and public health.

Locations

London, Greater London, United Kingdom

Patients applied

0 patients applied

Trial Officials

Kirill Aristovich

Principal Investigator

University College, London

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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