Software-based Modification of Hand Tremors in XR

Launched by NEUROSTORM, INC · Dec 18, 2022

Keywords

ClinConnect Summary

This study is testing whether a software feature inside virtual reality (VR) can help reduce hand tremors in people with Parkinson’s disease. Participants are randomly assigned to one of two VR setups: TSA-ON (VR with Tremor Stabilization Algorithms activated) or TSA-OFF (VR without the stabilization). They will perform a tremor test inside VR, and tremor severity will be measured with VR motion controllers. The main question is whether the TSA software lowers tremor right after the test. The study is designed so that participants and researchers don’t know which group each person is in, to keep results unbiased.

About 300 adults age 35–85 with Parkinson’s disease are expected to join. To qualify, you must be able to walk at least 5 minutes, have had no falls in the last 6 months, have enough hearing and vision to use VR, be able to complete online questionnaires, and give informed consent. Exclusions include visual-perceptual problems that would interfere with VR, dementia or significant cognitive impairment, or a history of stroke or other major neurological conditions. If eligible, you’d participate at NeuroStorm in New York and complete the tremor test in VR, with some follow-up measurements (5 minutes to up to 30 days afterward) to see if any tremor reduction lasts. The study is active and expected to continue through 2025.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Candidates eligible for our study will be 35 - 85 years, diagnosed with Parkinson's disease, with no falls within 6 months prior to the study, are able to walk for 5 minutes unassisted, have adequate hearing and vision capabilities, can comply with study requirements, have the ability to fill online questionnaires, and provide written informed consent to participate in the study.
• Exclusion Criteria:
• • Candidates that are ineligible for our study have visual-perceptual deficits that limit capacity to be in VR, have clinical diagnosis of dementia or other severe cognitive impairment as determined by a Mini-Mental State Examination score (MMSE) of less than 24, or have a history of stroke, traumatic brain injury or other neurological disorders