Effect of Optimized PEEP on Mechanical Ventilation During Robot Assisted Laparoscopic Prostatectomy

Launched by GANGNAM SEVERANCE HOSPITAL · Dec 21, 2022

Keywords

ClinConnect Summary

This clinical trial is exploring how different settings of a breathing support technique, called positive end-expiratory pressure (PEEP), can help improve breathing during robot-assisted surgery for prostate cancer. The study is looking at patients who are scheduled for this type of surgery and aims to find out if using a personalized PEEP setting for each patient can lead to better breathing results compared to a standard setting.

To participate in the trial, you need to be a male between 20 and 70 years old, scheduled for robotic prostate surgery, and have a body mass index (BMI) of 35 or less. The trial is currently recruiting participants, and if you qualify, you will receive either the standard PEEP or a tailored PEEP setting during your surgery. The research team will analyze your blood gases during the procedure to see which method works better for ventilation. It's important to note that patients with lung diseases or higher BMI, among other factors, would not be eligible to join this study.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • 1. 20 - 70 years of age who are scheduled for robotic assisted laparoscopic prostatectomy at the Department of Urology, Gangnam Severance Hospital,
• • 2. ASA-PS (American Society of Anesthesiology Body Rating) I-IlI,
• • 3. Patients with a BMI of 35 kg/m2 or less
• Exclusion Criteria:
• • 1. Patients with lung disease
• • 2. BMI \>35kg/m2
• • 3. Patients for whom positive end-tidal pressure cannot be applied (large bullae, severe cardiac disease)
• • 4. patient refusal