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Search / Trial NCT05676372

Single-Cell Transcriptomics of the Peritoneal Microenvironment of Colorectal PC

Launched by UNIVERSITY HOSPITAL, GHENT · Dec 22, 2022

Trial Information

Current as of July 22, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is looking at the cells in the abdominal area of patients with colorectal cancer that has spread to the peritoneum, which is the lining of the abdomen. By studying these cells, researchers hope to learn more about how this type of cancer behaves and how it can be treated. The trial is currently recruiting patients who are scheduled to undergo a specific type of surgery called CRS (Cytoreductive Surgery) combined with HIPEC (Hyperthermic Intraperitoneal Chemotherapy) for colorectal cancer that has spread to the peritoneum.

To be eligible for this trial, participants must be planning to have this surgery and should not have had a previous HIPEC or a related treatment called PIPAC. This means that the trial is open to any adult, regardless of gender, who meets these criteria. If you decide to participate, you can expect to provide samples during your surgery, which will help researchers gain insights into the cancer. This information could lead to better treatment options in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients undergoing CRS+HIPEC for PC of colorectal origin
  • Exclusion Criteria:
  • Previous HIPEC/PIPAC

About University Hospital, Ghent

University Hospital Ghent is a leading academic medical institution renowned for its commitment to advancing healthcare through innovative research and clinical trials. Located in Ghent, Belgium, the hospital is affiliated with Ghent University, fostering a collaborative environment that integrates cutting-edge medical research with high-quality patient care. With a diverse range of specialized departments and a dedicated team of researchers and clinicians, University Hospital Ghent is at the forefront of developing new therapies and improving treatment protocols, aiming to enhance patient outcomes and contribute to the global medical community.

Locations

Ghent, Oost Vlaanderen, Belgium

Patients applied

0 patients applied

Trial Officials

Wim Ceelen, MD, PhD

Principal Investigator

UZ Ghent

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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