ClinConnect ClinConnect Logo
Search / Trial NCT05676671

Microbiological Evaluation and Clinical 24-month Follow-up of Adhesive Systems on Carious Dentin

Launched by UNIVERSITY OF SAO PAULO · Jan 4, 2023

Trial Information

Current as of July 21, 2025

Completed

Keywords

Dental Caries Primary Tooth Dentin Bonding Agents Streptococci Randomized Controlled Trial

ClinConnect Summary

One hundred and four teeth from 40 children aged 6 to 9 years with one or two superficial deciduous molar cavities (occlusal and/or proximal-occlusal cavities), presenting high caries activity, were selected for this study. Fifty-three primary molars were selected for clinical/ radiographical evaluation and 51 primary molars were selected for microbiological evaluation in two different moments.

Restorative treatments For this part of the study, 53 primary molars were randomly divided into Clearfil SE Bond (CB, n = 29) and Clearfil SE Protect (CP, n = 24). All restorative treatments were pe...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • deciduous molars with one or two surfaces with caries lesions;
  • children without systemic problems and who were not using any medication;
  • absence of spontaneous pain, edema or fistula, and dental mobility;
  • radiographically, caries lesions in the inner half of the dentin thickness, absence of pulp contact with the lesion, absence of internal or external root resorption, and other changes suggestive of degenerative pulp conditions, such as radiolucencies in the furcation or periapical regions or widening of periodontal spaces.
  • Exclusion Criteria:
  • Caries lesions with involvement of the pulp or periodontal tissues;
  • Children with systemic problems.

About University Of Sao Paulo

The University of São Paulo (USP) is a prestigious public research university located in Brazil, renowned for its commitment to advancing knowledge and innovation in various fields, including medicine and health sciences. As a clinical trial sponsor, USP leverages its extensive academic resources, interdisciplinary expertise, and state-of-the-art facilities to facilitate groundbreaking research aimed at improving patient outcomes and addressing critical health challenges. The university's strong emphasis on ethical standards and regulatory compliance ensures that all clinical trials are conducted with the highest integrity, fostering collaboration among researchers, healthcare professionals, and the broader community to enhance scientific discovery and translate findings into practical applications.

Locations

Araçatuba, Sao Paulo, Brazil

Patients applied

0 patients applied

Trial Officials

Cristiane Duque, PhD

Principal Investigator

University of Sao Paulo

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Similar Trials