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Search / Trial NCT05676723

Thoracic Fluid Content by Bioimpedance-based Starling System

Launched by BICETRE HOSPITAL · Jan 6, 2023

Trial Information

Current as of June 04, 2025

Completed

Keywords

Acute Respiratory Distress Syndrome Shock Hemodynamic Monitoring Fluid Balance Pulmonary Edema

ClinConnect Summary

The Starling system is a completely non-invasive hemodynamic monitoring technique. It measures cardiac output through bioreactance. It also measures the mean transthoracic electric impedance (Z0) from which the thoracic fluid content (TFC) can be derived. The TFC is the only other variable that is provided by the system besides cardiac output and that is not inferred from it. The TFC is supposed to reflect the total content of fluid in the thorax and may include two of the variables that are commonly used for hemodynamic monitoring: the extravascular lung water (EVLW), which is the volume o...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age ≥ 18 y.o.
  • Hospitalization in an ICU
  • Monitoring by transpulmonary thermodilution already in place
  • Decision by clinicians in charge to perform volume expansion by saline or fluid removal by diuretics infusion and/or ultrafiltration ("Fluid" group)
  • Or presence of Acute Respiratory Distress Syndrome according to the Berlin definition ("ARDS" group)
  • Exclusion Criteria:
  • Refusal to join the study
  • In "Fluid" group, circulatory failure whose treatment cannot be postponed for ≥5 minutes (time required for the installation of Starling system).
  • Impossibility to paste bioreactance electrodes properly in the skin of the thorax.

About Bicetre Hospital

Bicetre Hospital, a renowned healthcare institution located in France, is dedicated to advancing medical research and patient care through innovative clinical trials. As a key player in the clinical research landscape, the hospital leverages its multidisciplinary expertise and state-of-the-art facilities to conduct rigorous studies across various therapeutic areas. With a commitment to ethical standards and patient safety, Bicetre Hospital fosters collaboration among healthcare professionals, researchers, and pharmaceutical partners to drive the development of new treatments and improve health outcomes for diverse patient populations.

Locations

Le Kremlin Bicêtre, île De France, France

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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