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Search / Trial NCT05676827

Pain, Central Sensitization and Psychoemotional State in Patients With Chronic Masticatory Muscle Pain

Launched by WROCLAW MEDICAL UNIVERSITY · Dec 22, 2022

Trial Information

Current as of August 22, 2025

Enrolling by invitation

Keywords

Tmd, Masticatory Muscle Pain, Central Sensitization

ClinConnect Summary

In this prospective cohort study, the study group will consist of 51 people with masticatory muscle pain lasting longer than 3 months, while the control group will involve 51 people without such disorder.

Muscle type of temporomandibular disorders will be diagnosed on the basis of validated and standardized DC/TMD protocol.

Additionally potential headaches will be assessed according to the ICHD-3, since coexistence of chronic masticatory muscle pain and headache is often observed.

Psychological aspects will be analyzed using validated questionnaires regarding depression (PHQ-9), anxiety ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria for study group:
  • Masticatory muscle pain for at least 3 months, based on DC/TMD, at least 18 y.o
  • Exclusion Criteria:
  • severe neurological or psychiatric diseases, use of drugs that may affect the neuromuscular system, alcohol or drug addiction, cancer or pregnancy, previous head surgery
  • Inclusion criteria for control group:
  • no pain in masticatory muscles, age of at least 18 y.o Exclusion criteria the same as for study group

About Wroclaw Medical University

Wrocław Medical University is a prestigious academic institution located in Wrocław, Poland, renowned for its commitment to advancing medical research and education. As a clinical trial sponsor, the university leverages its extensive expertise in healthcare and biomedical sciences to facilitate innovative research initiatives aimed at improving patient outcomes. With a strong emphasis on ethical practices and regulatory compliance, Wrocław Medical University collaborates with a diverse network of healthcare professionals and researchers to conduct rigorous clinical trials that contribute to the development of new therapies and enhance the understanding of various medical conditions. Its dedication to scientific excellence and patient safety positions the university as a key player in the global clinical research landscape.

Locations

Wrocław, , Poland

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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