Point-of-care Ultrasound Abnormalities in Eclampsia

Launched by UNIVERSITY OF CAPE TOWN · Jan 3, 2023

Keywords

ClinConnect Summary

This clinical trial is studying the use of point-of-care ultrasound (POCUS) to better understand the health issues related to eclampsia, a serious condition that can develop from preeclampsia during pregnancy. Eclampsia involves having seizures and can lead to complications that make managing anesthesia and delivery more challenging. The researchers want to see if POCUS can help identify important changes in the body that could indicate how severe the condition is and guide treatment decisions. They are particularly focusing on women who have been diagnosed with preeclampsia and have started having seizures.

To participate in this trial, women must be diagnosed with preeclampsia according to specific medical guidelines and have new-onset seizures. However, those with certain conditions, like severe lung or kidney disease, or a history of seizures, cannot join. Participants can expect to undergo assessments using ultrasound and possibly other tests to monitor their health during the study. This research aims to improve the care of pregnant women facing eclampsia, especially in settings where resources may be limited, such as in South Africa.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Diagnosis of preeclampsia following ACOG definition with new onset of tonic-clonic seizures.
• Exclusion Criteria:
• • Chronic pulmonary disease
• • Collagen disorders
• • HIV infection if CD4 count \<200 cells/ mm3
• • Chronic renal or hepatic disease
• • Urinary tract infection
• • Sepsis
• • Body mass index (BMI) \> 50 kg/m2
• • History of seizure disorder
• • Intracranial haemorrhage
• • History of benign or malignant intracranial neoplasia