Comparison Between Oral Melatonin and Hydroxyzine in Pediatric Patients Undergoing Adenotonsillectomy

Launched by MINIA UNIVERSITY · Jan 10, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at how effective two medications, oral Melatonin and Hydroxyzine, are in reducing anxiety in young children who are about to have a surgery called adenotonsillectomy, which involves removing the tonsils and adenoids. The goal is to see which medication better helps children feel calmer before their operation.

To participate in this study, children need to be between 3 and 10 years old, and they should be generally healthy, as those with chronic illnesses or developmental delays cannot join. If your child is chosen for the trial, they will receive either Melatonin or Hydroxyzine before their surgery to help with anxiety. It's important to know that children who have allergies to certain medications or conditions like acute porphyria will not be eligible to participate. If you think your child might qualify, this could be a helpful opportunity to support their comfort during a medical procedure.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. ASA: class l
• • 2. Sex: male and female
• • 3. Age: from 3 to 10 years old
• • 4. Children scheduled for adenotonsillectomy
• Exclusion Criteria:
• • 1. All children with a history of chronic illness, or developmental delay were excluded from the study
• • 2. History of an autoimmune disease
• • 3. Concurrent use of immunosuppressive treatment
• • 4. Sleep disturbances, speech or communication problems
• • 5. allergic to hydroxyzine, cetirizine, or other derivatives of piperazine, aminophylline, and ethylenediamine.
• • 6. hydroxyzine is contraindicated in patients with acute porphyria
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