Effects of Painful Compared to Painless Manual Therapy on Pain Processing in University Students With Neck Pain
Launched by JOSUE FERNANDEZ CARNERO · Dec 27, 2022
Trial Information
Current as of August 14, 2025
Completed
Keywords
ClinConnect Summary
The mechanical stimulus produced in manual therapy (MT) techniques elicits neurophysiological responses within the peripheral and central nervous system responsible for pain inhibition. Almost all types of MT elicit a neurophysiological response that is associated with the descending pain modulation circuit. But it has not been demonstrated whether this inhibition occurs through a conditioned pain modulation mechanism generated by the pain that manual therapy techniques may elicit in the patient.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • University students
- • Chronic neck pain (persistent pain \> 3 months almost every day of the week) or recurrent neck pain (repeated episodes of neck pain starting \> 3 months ago with pain-free periods)
- • Non-specific neck pain (pain in the neck region that is not attributable to a known specific such as herniated disc, myelopathy, fractures, spinal stenosis, neoplasm etc. nor is it associated with traumatic causes such as whiplash)
- • Mean NRS score the last week \> 2/10 and presence of pain on the day of assesment and treatment
- Exclusion Criteria:
- • Signs of radiculopathy or neuropathic pain
- • Neck surgeries
- • Inflammatory rheumatic
- • Neurological, cardiorespiratory, oncological or psychiatric disease
- • Pregnancy
- • Not being able to read Spanish in order to fill in the questionnaires
About Josue Fernandez Carnero
Josue Fernandez Carnero is a dedicated clinical trial sponsor with a strong commitment to advancing medical research and improving patient outcomes. With extensive experience in managing and overseeing clinical studies, Josue emphasizes rigorous adherence to ethical standards and regulatory compliance. His focus encompasses a range of therapeutic areas, utilizing innovative methodologies to ensure the integrity and reliability of trial results. By fostering collaboration among multidisciplinary teams, Josue strives to accelerate the development of safe and effective treatments that address unmet medical needs.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Alcorcón, Madrid, Spain
Patients applied
Trial Officials
Josué Fernández Carnero, PhD
Principal Investigator
Universidad Rey Juan Carlos
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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