Maternal Oxygen Supplementation for Intrauterine Resuscitation

Launched by WASHINGTON UNIVERSITY SCHOOL OF MEDICINE · Dec 27, 2022

Keywords

ClinConnect Summary

This clinical trial is studying whether providing extra oxygen to mothers during labor can help improve the condition of babies who may be experiencing stress or low oxygen levels. The researchers want to find out if giving supplemental oxygen is safe and effective, especially since there are different opinions among medical professionals about its use. The trial will compare the effects of oxygen supplementation to regular room air for mothers whose babies show signs of distress during continuous fetal monitoring.

To participate in this study, women need to be at least 37 weeks pregnant with a single baby, either in spontaneous labor or being induced. They should be able to communicate in English or Spanish and plan to have continuous monitoring of their baby's heartbeat during labor. Participants will be randomly assigned to receive either supplemental oxygen or room air, and the study aims to gather important safety data to help guide future recommendations for using oxygen in labor and delivery. This information is crucial for ensuring that any treatments used during pregnancy meet strict safety standards.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Singleton gestation
• • Gestational age\>=37 weeks
• • Spontaneous labor or induction of labor
• • English or spanish speaking
• • Planned continuous fetal monitoring
• Exclusion Criteria:
• • Preterm gestation
• • Major fetal anomaly
• • Multiple gestation
• • Category III fetal monitoring at time of admission
• • Maternal hypoxia \<95%
• • Planned or scheduled cesarean delivery Excluded from randomization if receiving nitrous oxide for analgesia at time of randomization.