US and MRI of the Forefoot: Intermetatarsal Bursitis or Morton's Neuroma
Launched by RIGSHOSPITALET, DENMARK · Jan 5, 2023
Trial Information
Current as of August 29, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
This clinical trial is investigating two conditions that can cause pain in the forefoot: intermetatarsal bursitis and Morton's neuroma. Researchers want to see how often these conditions occur in people experiencing metatarsalgia, which means pain in the ball of the foot. To do this, they will use ultrasound and MRI scans to look closely at the feet of both patients who have foot pain and healthy volunteers.
To participate in this study, you need to be over 18 years old and have pain in the space between your toes. Unfortunately, if you have any open wounds or infections in your foot, or if you’ve had major foot injuries or surgeries, you won't be eligible. The study is currently looking for participants, and anyone who joins can expect to undergo some imaging tests to help learn more about these foot conditions. This trial is important because it aims to improve our understanding of foot pain, which can help doctors provide better treatment options in the future.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age \> 18 years
- • Pain in an intermetatarsal space (patient group)
- Exclusion Criteria:
- • Age \<18 years
- • Open wounds or ongoing infection in the forefoot at the time of examination
- • Persons with contraindications to participate in MRI scan
- • Persons with a history of significant trauma in the forefoot, e.g. any fracture or previous surgeries in the forefoot
- • Persons who have previously received treatment for Morton's neuroma in the same foot, e.g. injection (within 6 months) or operation (anytime)
- • Persons with severely impaired renal function (GFR \<30 ml/min)
- • Persons with a systemic inflammatory condition like rheumatoid arthritis, due to clinically silent intermetatarsal bursitis in this group (control group)
About Rigshospitalet, Denmark
Rigshospitalet, located in Copenhagen, Denmark, is one of the leading hospitals in Scandinavia and a prominent center for clinical research and innovation. As a key academic institution affiliated with the University of Copenhagen, Rigshospitalet is dedicated to advancing healthcare through rigorous clinical trials and groundbreaking research across various medical disciplines. The hospital’s commitment to excellence is reflected in its multidisciplinary approach, collaboration with international research networks, and focus on improving patient outcomes through evidence-based practices. With state-of-the-art facilities and a team of highly qualified professionals, Rigshospitalet plays a crucial role in translating scientific discoveries into effective treatments and therapies.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Copenhagen, , Denmark
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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