Accuracy of Deep Inferior Epigastric Artery Perforator Mapping - Color Doppler Ultrasound Versus CT Angiography
Launched by ST. ANNE'S UNIVERSITY HOSPITAL BRNO, CZECH REPUBLIC · Jan 12, 2023
Trial Information
Current as of August 02, 2025
Completed
Keywords
ClinConnect Summary
A blinded, randomized, prospective clinical trial was performed involving women over 18 years undergoing 2021 unilateral or bilateral breast reconstruction with an abdominal free flap. The inclusion of the mapping of major perforators as a part of preoperative deep inferior epigastric perforator (DIEP) flap planning reduces the operating time and complication rate. According to recent meta-analyses computed tomographic angiography (CTA) brings the most advantages; however, only a few studies comprising colour Doppler ultrasonography (CDU) were included with several biases in addition. Espec...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • female;
- • aged 18 to 65 years;
- • undergoing uni- or bilateral breast free flap reconstruction harvested from the lower abdomen;
- • signed informed consent to participate in the study.
- Exclusion Criteria:
- • history of allergy to iodinated contrast material;
- • history of abdominoplasty;
- • Body Mass index \> 35;
- • active oncological disease ;
- • Karnofsky Performance Status \< 50;
- • change of the reconstructive method as a result of the preoperative mapping;
- • non-standard performed CTA examination.
About St. Anne's University Hospital Brno, Czech Republic
St. Anne's University Hospital Brno, located in the Czech Republic, is a leading academic medical center renowned for its commitment to advancing healthcare through innovative clinical research and comprehensive patient care. As a prominent sponsor of clinical trials, the hospital leverages its multidisciplinary expertise and state-of-the-art facilities to facilitate high-quality research across various medical fields. With a focus on collaboration and ethical standards, St. Anne's University Hospital Brno aims to translate scientific discoveries into effective treatments, ultimately enhancing patient outcomes and contributing to the global medical community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Brno, , Czechia
Patients applied
Trial Officials
Libor Streit, MD, PhD.
Principal Investigator
St. Anne´s University Hospital Brno
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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