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Search / Trial NCT05687188

Evaluating Obesity-Mediated Mechanisms of Pancreatic Carcinogenesis in Minority Populations

Launched by H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE · Jan 6, 2023

Trial Information

Current as of September 30, 2025

Recruiting

Keywords

Pancreas Biomarkers Health Disparities

ClinConnect Summary

This clinical trial is exploring how obesity may affect the development of pancreatic cancer, particularly in minority groups. Researchers want to understand the specific ways that being overweight might lead to this type of cancer. The study is currently looking for participants, specifically adults aged 18 and older who identify as African American or Non-Hispanic White, and who have been referred to certain medical centers in Florida or Mississippi because there is a concern about pancreatic tumors.

If you or a loved one are eligible and decide to participate, you will be part of a team trying to uncover important information about pancreatic cancer and obesity. Participants can expect to undergo assessments and provide information that may help improve understanding and treatment of pancreatic cancer in the future. It's important to note that individuals under 18 years old or those with no suspicion or diagnosis of a pancreatic tumor cannot take part in this study.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adults 18 years of age or older at time of signing informed consent
  • Patients who self-report as African American, Non-Hispanic White
  • Patients who present to the gastrointestinal (GI) clinic, surgery, or endoscopy at a participating Florida Pancreas Collaborative (FPC) site or the University of Mississippi Medical Center (UMMC) with a clinical suspicion or diagnosis of a pancreatic tumor.
  • Exclusion Criteria:
  • Patient under 18 years of age
  • Has no suspicion or diagnosis of a pancreatic cancer or tumor
  • Self-reported race/ethnicity other than African American or Non-Hispanic White.

About H. Lee Moffitt Cancer Center And Research Institute

H. Lee Moffitt Cancer Center and Research Institute is a leading institution dedicated to cancer research, treatment, and education, recognized for its commitment to advancing cancer care through innovative clinical trials and groundbreaking research. As a National Cancer Institute-designated Comprehensive Cancer Center, Moffitt integrates cutting-edge science with patient-centered care, offering a multidisciplinary approach to cancer treatment. The center is at the forefront of developing novel therapies and improving outcomes for patients, emphasizing collaboration between researchers and clinicians to translate scientific discoveries into effective treatments. Through its extensive clinical trial programs, Moffitt aims to enhance the understanding of cancer biology and provide patients with access to the latest therapies and interventions.

Locations

Tampa, Florida, United States

Jackson, Mississippi, United States

Patients applied

0 patients applied

Trial Officials

Jennifer Permuth, PhD, MS

Principal Investigator

Moffitt Cancer Center

Mokenge Malafa, MD

Principal Investigator

Moffitt Cancer Center

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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