Clinical Study of Curcumin in Preventing Postoperative Adhesion of Bilateral Vocal Cords

Launched by EYE & ENT HOSPITAL OF FUDAN UNIVERSITY · Jan 15, 2023

Keywords

ClinConnect Summary

This clinical trial is studying the use of curcumin, a natural substance found in turmeric, to prevent the formation of scar tissue (adhesions) on the vocal cords after surgery. This is important for patients who have conditions affecting their vocal cords, such as growths or strictures, and who are undergoing surgery to remove these issues. The trial aims to see if applying curcumin directly to the surgery sites can help improve recovery and vocal function.

To participate in this trial, patients need to have a specific vocal cord condition and be scheduled for surgery to treat it. Those who have other serious health issues, cannot follow up after surgery, or have certain allergies may not be eligible. If someone joins the trial, they can expect to have curcumin applied to their vocal cords after surgery and will be monitored for their recovery. This study is currently looking for participants of all ages, and it represents a promising step towards better treatment options for vocal cord issues.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients with bilateral vocal cord diseases who are going to undergo resection of bilateral vocal cord lesions endoscopically.
• • 2. Patients with bilateral vocal cord adhesion who are going to undergo incision of bilateral vocal cord adhesion endoscopically.
• Exclusion Criteria:
• • 1. Patients with other laryngeal diseases.
• • 2. Patients with cardiac and pulmonary insufficiency.
• • 3. Patients unable to cooperate with the follow-up on time after surgery.
• • 4. Patients who refuse to sign the informed consent after notification.
• • 5. Patients who have a severe allergic disease or allergic history to a variety of drugs.
• • 6. Other circumstances that are not appropriate to be included in the clinical trial.