Discovering Novel Cancer Treatment Options Using a Comprehensive NGS-based Molecular Testing Panel in the Community Setting ("DINOSAur")

Launched by GLENDALE ADVENTIST MEDICAL CENTER D/B/A ADVENTIST HEALTH GLENDALE · Jan 10, 2023

Keywords

ClinConnect Summary

The DINOSAur trial is exploring new treatment options for patients with advanced solid tumors (stage III and IV cancer). The goal of this study is to identify specific markers in cancer cells that can help doctors choose the best treatments for each individual patient. By using a special test that looks at the genes and proteins in the tumors, the trial aims to match patients with therapies that are most likely to work for them.

To participate in this study, patients need to be at least 18 years old, have a diagnosis of stage III or IV solid tumors, and have not yet started any treatment for their cancer. They should be able to provide consent and are encouraged to share their medical records with the research team. Participants can expect to undergo some additional tests as part of their usual cancer care, and their progress will be closely monitored. This trial is currently recruiting patients, and it provides a unique opportunity to explore personalized cancer treatment approaches in a community setting.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients who have given informed consent in accordance with the methods and procedures of this study
• • Diagnosis of cancer (stage 3 and stage 4; solid tumors only) requiring medical care
• • Patients who have not received treatment related to his/her cancer
• • Patients who are willing to sign a release of medical records to the research team
• • Male and female patients ≥18 years of age
• • Patients under oncology care of a participating site
• • Sufficient clinical status for collection of biospecimen samples within usual care
• • Patients who have insurance coverage for CMT
• Exclusion Criteria:
• • Patients considered minors in the jurisdiction where the protocol is conducted.
• • Patients who are prisoners and pregnant women.
• • Patients who cannot provide consent and did not sign a power of attorney.