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Search / Trial NCT05693220

Sperm Preparation Prior to Intrauterine Insemination Study

Launched by UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · Jan 12, 2023

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Intrauterine Insemination Insemination Fertility Infertility

ClinConnect Summary

The Sperm Preparation Prior to Intrauterine Insemination Study is a research trial looking at two different methods of preparing sperm before a procedure called intrauterine insemination (IUI), which is often used to help couples facing infertility issues. The trial aims to find out which method—density gradient centrifugation or microfluidic sperm sorting—results in better pregnancy outcomes. This study is currently recruiting participants, and it is open to individuals who are assigned female at birth and are under 41 years old, as long as they have not previously undergone IUI and do not have any major health problems that could affect their ability to participate.

If you decide to join this study, you will be randomly assigned to one of the two sperm preparation methods and will then proceed with the IUI procedure. The goal is to see how well each method works in helping achieve pregnancy. Participation in this trial could contribute to a better understanding of fertility treatments and may help others in similar situations in the future. Please note, only English speakers can participate, and those who have used frozen donor sperm or have already had IUI will not be eligible.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients undergoing intrauterine insemination
  • Patient assigned female at birth with age \<41
  • Exclusion Criteria:
  • Any significant disease or psychiatric disorder that would interfere with the consenting process
  • Prior intrauterine insemination
  • Use of frozen donor sperm
  • Non-English speaker

About University Of California, San Francisco

The University of California, San Francisco (UCSF) is a leading academic institution renowned for its commitment to advancing healthcare through innovative research and clinical trials. With a focus on translating scientific discoveries into effective therapies, UCSF collaborates with a diverse array of stakeholders, including healthcare professionals, industry partners, and patient communities. The university's research programs emphasize interdisciplinary approaches and leverage cutting-edge technology to address complex medical challenges. As a sponsor of clinical trials, UCSF is dedicated to maintaining the highest standards of ethical conduct and scientific rigor, ensuring the safety and well-being of participants while contributing to the broader medical knowledge base.

Locations

San Francisco, California, United States

Patients applied

0 patients applied

Trial Officials

Mitchell Rosen, MD

Principal Investigator

University of California, San Francisco

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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