Preterm Neonates Brain Ultrasound With CEUS and Elastography

Launched by TURKU UNIVERSITY HOSPITAL · Jan 20, 2023

Keywords

ClinConnect Summary

This clinical trial is focused on understanding how well the brains of preterm babies are functioning as they approach their due date. Researchers want to see how blood flow and the elasticity (or stretchiness) of the brain tissue compare with results from a special type of brain scan called magnetic resonance imaging (MRI). To do this, they will use advanced ultrasound techniques that involve a contrast agent, which helps to visualize the blood flow better. The study is taking place at the Neonatal Intensive Care Unit (NICU) of Turku University Hospital and is currently looking for participants.

To be eligible for the study, babies must be preterm and scheduled for an MRI at their expected due date. However, certain conditions may exclude them from participating, such as having a known genetic condition, serious birth defects needing surgery, or issues related to their heart or lungs. Parents can expect their child to undergo both ultrasound and MRI tests, which are safe and commonly used in medical settings. This research aims to improve our understanding of brain health in preterm infants, which could lead to better care and outcomes for these vulnerable babies.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Preterm neonates attending brain MR-imaging at term
• Exclusion Criteria:
• • Pre-known genetic disease
• • Difficult congenital malformations that need surgical treatment
• • Central nervous system tumors
• • Weight less than 2,5 kg during examination
• • Medical history of SonoVue hypersensitivity
• • Uncontrolled systemic hypertension
• • Systolic pulmonary artery pressure \> 90 mmHg
• • Unstable cardiovascular state