Effect of High-intensity Interval Training on Low-grade Systemic Inflammation in Obese Young Adults.

Launched by UNIVERSITY OF GUADALAJARA · Jan 25, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how high-intensity interval training (HIIT) can help reduce low-grade inflammation in young adults who are obese. Low-grade inflammation is a condition where the body has mild but chronic inflammation, which can be harmful and is often linked to obesity. The trial will involve participants aged 18 to 30 with a body mass index (BMI) of 30 to 39.9, and they will need access to a computer or smartphone to participate. Participants will be randomly assigned to either a HIIT group, which will perform short bursts of intense exercise, or a control group that will engage in moderate-intensity exercise.

Over the course of two months, both groups will meet three times a week for their workouts. The researchers will assess participants’ health through various tests at the start of the trial, and again at four weeks and eight weeks. It's important to note that certain individuals, such as those with specific health conditions or who smoke, will not be eligible to participate. This study aims to find out if regular high-intensity exercise can effectively lower inflammation levels, which could lead to better health outcomes for obese young adults.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Young adults, between 18 and 30 years.
• • BMI ≥ 30-39.9 kg/m2
• • How signed the informed consent
• • Additionally, it is necessary that they have computer equipment, electronic tablet, or smart cell phone, as well as access to electricity and the Internet.
• Exclusion Criteria:
• • Participants who smoke
• • Presence of any of the following comorbidities: hypothyroidism, type 1 diabetes mellitus, type 2 diabetes mellitus, arterial hypertension, oncological pathology, immunological or rheumatic diseases.
• • Consumption of nitrates and anticalcium drugs during the 4 days prior to the start of the investigation and beta blockers, hypoglycemic drugs 7 days prior to the start of the intervention.
• • Pregnant or breastfeeding
• • Men who consume more than 40 g/day of alcohol or women who consume more than 20 g/day
• • Postural and biomechanical alterations (knee, foot or spine)
• • Previous diagnosis and less than 6 months of COVID 19
• • Previous diagnosis of HIV +
• • Previous diagnosis of periodontal disease