A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE
Launched by JANSSEN RESEARCH & DEVELOPMENT, LLC · Jan 19, 2023
Trial Information
Current as of July 23, 2025
Recruiting
Keywords
ClinConnect Summary
The LIBREXIA-STROKE trial is studying a new medication called milvexian to see if it can help prevent another ischemic stroke in people who have recently experienced one or a high-risk transient ischemic attack (TIA), which is sometimes called a "mini-stroke." In this study, participants will be randomly assigned to receive either milvexian or a placebo (a substance with no active medication) to compare how well each option works.
To be eligible for this trial, participants must have had an ischemic stroke or a TIA within the last 48 hours and meet specific health criteria, such as having a certain level of neurological symptoms and being willing to follow the trial guidelines. Participants will be monitored closely and can expect to adhere to some lifestyle restrictions during the study. It's important to note that women in the study must not be pregnant or planning to become pregnant for a short time after the study medication. If you or a loved one are interested in participating, please talk to a healthcare provider for more information.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Ischemic Stroke: a neurological deficit attributable to an acute brain infarction and national institute of health stroke score scale (NIHSS) score less than or equal to (\<=) 7 and at least 1 of the following: persistent signs or symptoms of the ischemic event at the time of randomization, or acute, ischemic brain lesion determined by standard-of-care neuroimaging, or participant underwent thrombolysis or thrombectomy, or transient ischemic attack (TIA): acute onset neurological deficit attributable to focal ischemia of the brain by history or examination, with complete symptom resolution of the deficit and no brain infarction on neuroimaging (example, computed tomography (CT) scan or magnetic resonance imaging (MRI), performed as part of standard medical practice), and ABCD2 Score greater than or equal to (\>=) 6
- • Participants will be randomized as soon as possible after determining eligibility and within 48 hours of onset of event.
- • Current or planned antiplatelet treatment per international and/or local guidelines. If acetyl salicylic acid (ASA) is used, it will be limited to low dose (75 to 100 milligrams (mg)/day). Loading dose of antiplatelet agents (including ASA) are allowed per standard-of-care
- • A female participant must agree not to be pregnant, breastfeeding, or planning to become pregnant until 4 days (5 half lives) after the last dose of study intervention
- • Willing and able to adhere to the lifestyle restrictions specified in this protocol
- Exclusion Criteria:
- • Prior history of intracranial hemorrhage except subarachnoid hemorrhage greater than (\>) 1 year prior with adequate treatment
- • The index stroke or TIA is considered to have a cardio-embolic etiology based on local standard-of-care investigations and for which guidelines recommend anticoagulation
- • The index stroke or TIA considered to have another known cause, not related to athero-thrombotic sources (treatment of acute stroke trial \[TOAST\] Other Determined Etiology), based on local standard-of-care investigations
- • Increased risk of bleeding, including clinically significant bleeding within the previous 3 months or known bleeding diathesis or known activated partial thromboplastin time (aPTT) prolongation or spinal cord hemorrhage or retinal hemorrhage
- • Current active liver disease, eg, acute hepatitis, known cirrhosis, including participants receiving antiviral treatment for hepatitis
- • Known allergies, hypersensitivity, or intolerance to milvexian or its excipients
About Janssen Research & Development, Llc
Janssen Research & Development, LLC, a subsidiary of Johnson & Johnson, is a leading pharmaceutical company dedicated to advancing innovative therapies in multiple therapeutic areas, including oncology, immunology, neuroscience, infectious diseases, and cardiovascular health. With a strong commitment to scientific excellence and patient-centered research, Janssen leverages cutting-edge technology and collaborative partnerships to drive the development of transformative treatments. The company is focused on addressing unmet medical needs through rigorous clinical trials and a robust pipeline, aiming to improve health outcomes and enhance the quality of life for patients worldwide.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Evanston, Illinois, United States
Laquenexy, , France
Ciudad Autonoma De Buenos Aires, , Argentina
Cordoba, , Argentina
Cordoba, , Argentina
Kobe Shi, , Japan
Katowice Ochojec, , Poland
Lisboa, , Portugal
Aurora, Colorado, United States
Pensacola, Florida, United States
Silver Spring, Maryland, United States
La Mesa, California, United States
West Palm Beach, Florida, United States
Mons, , Belgium
Campo Largo, , Brazil
Rijeka, , Croatia
Muenchen, , Germany
Iloilo, , Philippines
Lipa City, , Philippines
San Fernando, , Philippines
Malaga, , Spain
Lincoln, , United Kingdom
Chia Yi City, , Taiwan
Hualien, , Taiwan
Thessaloniki, , Greece
New Delhi, , India
Surat, , India
Varanasi, , India
Tel Aviv, , Israel
Nishinomiya Shi, , Japan
Toyohasi Shi, , Japan
Tongaat, , South Africa
Worcester, , South Africa
Eugene, Oregon, United States
Changchun, Jilin, China
Dalian, Liaoning, China
Pingxiang, Jiangxi, China
Shenyang, Liaoning, China
Shijiazhuang, Hebei, China
Osaka, , Japan
Temple Terrace, Florida, United States
Bern, , Switzerland
Dundee, , United Kingdom
York, , United Kingdom
Changsha, , China
Chengdu, , China
Luoyang, , China
Pingxiang, , China
Shantou, , China
Besançon Cedex, , France
Laquenexy, , France
Limoges, , France
Kawasaki City, , Japan
Sapporo Shi, , Japan
Incheon, , Korea, Republic Of
Seoul, , Korea, Republic Of
Uijeongbu Si, , Korea, Republic Of
Chicago, Illinois, United States
Barcelona, , Spain
Curitiba, , Brazil
Surat, , India
Tokyo, , Japan
New Lambton Heights, , Australia
Hamburg, , Germany
Pune, , India
Fukuoka Shi, , Japan
Wejherowo, , Poland
Durban, , South Africa
Istanbul, , Turkey
Izmir, , Turkey
Leuven, , Belgium
Athens, , Greece
Bursa, , Turkey
Izmir, , Turkey
Newark, New Jersey, United States
Antwerpen, , Belgium
Zagreb, , Croatia
Kasugai Shi, , Japan
Kortrijk, , Belgium
Santa Monica, California, United States
Nanyang, Henan, China
Tonghua, Jilin, China
Yantai, Shandong, China
Torrance, California, United States
Budapest, , Hungary
Bikaner, , India
Dzialdowo, , Poland
Jingdezhen, , China
Indianapolis, Indiana, United States
Niagara Falls, Ontario, Canada
Shenyang, , China
Praha 6, , Czechia
Kumamoto, , Japan
Sungai Buloh, , Malaysia
Tiwi, , Australia
Toyota Shi, , Japan
Ahmedabad, , India
Plovdiv, , Bulgaria
Santiago, , Chile
Nashik, , India
Komoro Shi, , Japan
Preston, , United Kingdom
São Paulo, , Brazil
Roma, , Italy
Asheville, North Carolina, United States
Washington, District Of Columbia, United States
Vac, , Hungary
Malmoe, , Sweden
Ishikawa, , Japan
Linfen, Shanxi, China
Sejong Si, , Korea, Republic Of
Houston, Texas, United States
Cordoba, , Spain
Cordoba, , Argentina
New Westminster, British Columbia, Canada
Beijing, , China
Olomouc, , Czechia
Brest Cedex, , France
Tokyo, , Japan
Tsukuba City, , Japan
Kunming, , China
Urumchi, , China
Wuxi, , China
Banska Bystrica, , Slovakia
Tainan, , Taiwan
Chiangmai, , Thailand
Nashville, Tennessee, United States
Matsubara Shi, , Japan
Yonezawa Shi, , Japan
Pikeville, Kentucky, United States
Cordoba, , Spain
Mangalore, , India
Thiruvananthapuram, , India
Beijing, , China
Osaka, , Japan
East Kilbride, , United Kingdom
Bronx, New York, United States
Brasilia, , Brazil
Changchun, , China
Changsha, , China
Lanzhou, , China
Jinan, Shandong, China
Nanyang, , China
Thessaloniki, , Greece
Wenzhou, , China
Shimonoseki Shi, , Japan
Písek, , Czechia
Budapest, , Hungary
Ankara, , Turkey
Skarzysko Kamienna, , Poland
St. Gallen, , Switzerland
Kurume Shi, , Japan
Paris, , France
Vishakhapatnam, , India
Pune, , India
Lublin, , Poland
Salamanca, , Spain
Joliet, Illinois, United States
Rockford, Illinois, United States
Louisville, Kentucky, United States
Bethesda, Maryland, United States
Grand Rapids, Michigan, United States
Fayetteville, Arkansas, United States
Saint Louis, Missouri, United States
Berkeley, California, United States
San Diego, California, United States
San Diego, California, United States
Thousand Oaks, California, United States
Newark, Delaware, United States
Bradenton, Florida, United States
Delray Beach, Florida, United States
Saint Louis, Missouri, United States
Camden, New Jersey, United States
Brooklyn, New York, United States
New York, New York, United States
Sleepy Hollow, New York, United States
Miami, Florida, United States
Miami, Florida, United States
Cleveland, Ohio, United States
Portland, Oregon, United States
Portland, Oregon, United States
Allentown, Pennsylvania, United States
Paoli, Pennsylvania, United States
Chattanooga, Tennessee, United States
Nashville, Tennessee, United States
Austin, Texas, United States
Port Charlotte, Florida, United States
Dallas, Texas, United States
Sarasota, Florida, United States
Glenview, Illinois, United States
Dendermonde, , Belgium
Edegem, , Belgium
Gent, , Belgium
El Paso, Texas, United States
Brasília, , Brazil
Fort Worth, Texas, United States
Seattle, Washington, United States
Buenos Aires, , Argentina
Buenos Aires, , Argentina
Ciudad Autonoma Buenos Aires, , Argentina
Ciudad Autonoma De Buenos Airess, , Argentina
Ciudad De Buenos Aires, , Argentina
Curitiba, , Brazil
Niteroi, , Brazil
Porto Alegre, , Brazil
Cordoba, , Argentina
Mar Del Plata, , Argentina
Mendoza, , Argentina
Salta, , Argentina
Bankstown, , Australia
Sao Jose Do Rio Preto, , Brazil
Campbelltown, , Australia
Sao Paulo, , Brazil
São Paulo, , Brazil
Stara Zagora, , Bulgaria
Midland, , Australia
Mississauga, Ontario, Canada
Concepcion, , Chile
Santiago, , Chile
St Leonards, , Australia
Modling, , Austria
Santiago, , Chile
Arlon, , Belgium
Talcahuano, , Chile
Temuco, , Chile
Baotou, , China
Brussels, , Belgium
Chongqing, , China
Beijing, , China
Dalian, , China
Changzhou, , China
Dalian, , China
Daqing, , China
Dongguan, , China
Guangzhou, , China
Guangzhou, , China
Usti Nad Labem, , Czechia
Aarhus, , Denmark
Hangzhou, , China
Copenhagen Nv, , Denmark
Copenhagen, , Denmark
Herlev, , Denmark
Odense C, , Denmark
Hefei, , China
Tallinn, , Estonia
Tartu, , Estonia
Lappeenranta, , Finland
Huhehaote, , China
Jiaozuo, , China
Nanjing, , China
Aix En Provence Cedex 01, , France
Le Kremlin Bicetre Cedex, , France
Le Mans Cedex 9, , France
Nice Cedex 1, , France
Rennes Cedex 09, , France
Bremen, , Germany
Deggendorf, , Germany
Dresden, , Germany
Guenzburg, , Germany
Hannover, , Germany
Muenster, , Germany
New Territories, , Hong Kong
Budapest, , Hungary
Budapest, , Hungary
Budapest, , Hungary
Vac, , Hungary
Amritsar, , India
Hyderabad, , India
Hyderabad, , India
Lucknow, , India
Mysore, , India
New Delhi, , India
Yerushalayim, , Israel
Aichi, , Japan
Pingxiang, , China
Aki Gun, , Japan
Chiba Shi, , Japan
Chiba, , Japan
Chikushino Shi, , Japan
Qingdao, , China
Shandong, , China
Shenyang, , China
Tai'an, , China
Fukuoka, , Japan
Fukuoka, , Japan
Taizhou, , China
Wuxi, , China
Xi'an, , China
Zabok, , Croatia
Chomutov, , Czechia
Praha 10, , Czechia
Nagano Shi, , Japan
Praha 4, , Czechia
Gyeonggi Do, , Korea, Republic Of
Tokyo, , Japan
Aguascalientes, , Mexico
Vila Real, , Portugal
Arad, , Romania
Oradea, , Romania
Levoca, , Slovakia
Liptovsky Mikulas, , Slovakia
Lucenec, , Slovakia
Nitra, , Slovakia
Sabadell, , Spain
Salamanca, , Spain
Zaragoza, , Spain
Stockholm, , Sweden
Ciudad De Mexico, , Mexico
Culiacan, , Mexico
Mexico, , Mexico
Bern, , Switzerland
Monterrey, , Mexico
Puebla, , Mexico
Christchurch, , New Zealand
Hamilton, , New Zealand
Genève, , Switzerland
Baguio City, , Philippines
Kaohsiung, , Taiwan
Constanta, , Romania
Margate, , United Kingdom
Ho Chi Minh, , Vietnam
Davao City, , Philippines
Ilocos Sur, , Philippines
Iloilo City, , Philippines
Manila, , Philippines
Warszawa, , Poland
Warszawa, , Poland
Lisboa, , Portugal
Long Beach, California, United States
Chelmie, , Poland
Detroit, Michigan, United States
Loures, , Portugal
Pragal, , Portugal
Vila Nova De Gaia, , Portugal
Ludhiana, , India
Warszawa, , Poland
Turku, , Finland
Sacramento, California, United States
Sarasota, Florida, United States
Boston, Massachusetts, United States
East Lansing, Michigan, United States
Cordoba, , Argentina
Camperdown, , Australia
Belo Horizonte, , Brazil
Porto Alegre, , Brazil
Montana, , Bulgaria
Sofia, , Bulgaria
Guangzhou, , China
Hangzhou, , China
Lanzhou, , China
Verona, , Italy
Shijiazhuang, , China
ålborg, , Denmark
Nanjing, , China
Tallinn, , Estonia
Hus, , Finland
Kistarcsa, , Hungary
Kisvarda, , Hungary
Miskolc, , Hungary
Dunaujvaros, , Hungary
Vilnius, , Lithuania
Jaipur, , India
Kuala Lumpur, , Malaysia
Bucuresti, , Romania
Kragujevac, , Serbia
Ludhiana, , India
Bratislava, , Slovakia
Oakland, California, United States
Fukuoka, , Japan
Everett, Washington, United States
Cordoba, , Argentina
Palo Alto, California, United States
Torrance, California, United States
Naharya, , Israel
Lecce, , Italy
Nagoya Shi, , Japan
Sao Paulo, , Brazil
Sofia, , Bulgaria
Okayama Shi, , Japan
Fitzroy, , Australia
Kosice, , Slovakia
Levice, , Slovakia
Petrzalka, , Slovakia
Albacete, , Spain
Herning, , Denmark
Omaha, Nebraska, United States
Gifu, , Japan
Adelaide, , Australia
Randwick, , Australia
Osaka Shi, , Japan
Lethbridge, Alberta, Canada
Sofia, , Bulgaria
Federal, , Argentina
Klagenfurt, , Austria
Santiago, , Chile
Marseille Cedex 05, , France
Tatabanya, , Hungary
Baoji, , China
Fukuoka, , Japan
Irvine, California, United States
Bangalore, , India
Modena, , Italy
Buenos Aires, , Argentina
San Francisco, California, United States
Greeley, Colorado, United States
Caba, , Argentina
Ciudad Autonoma Buenos Aires, , Argentina
Changchun, , China
Nanchang, , China
Liverpool, , Australia
Botucatu, , Brazil
Nanyang, , China
N.T., , Hong Kong
Kolkata, , India
Foligno, , Italy
Kumamoto, , Japan
Kure Shi, , Japan
Nagasaki Shi, , Japan
Tokyo, , Japan
Toyoake, , Japan
Breda, , Netherlands
Debrecen, , Hungary
Coimbatore, , India
Fort Wayne, Indiana, United States
Dortmund, , Germany
Chenzhou, , China
Gurgaon, , India
Urayasu Shi, , Japan
Nashik, , India
New Delhi, , India
Targu Mures, , Romania
Taoyuan County, , Taiwan
Bangkok, , Thailand
Lucenec, , Slovakia
Halifax, , United Kingdom
Abington, Pennsylvania, United States
Changsha, , China
Hanoi, , Vietnam
Qiqihaer, , China
Taiyuan, , China
Córdoba, , Argentina
Gyor, , Hungary
Gwangju, , Korea, Republic Of
Guimarães, , Portugal
Wirral, , United Kingdom
Launceston, , Australia
Edmonton, Alberta, Canada
Hatsukaichi, , Japan
Kyoto Shi, , Japan
Nis, , Serbia
Norfolk, Virginia, United States
Lake Success, New York, United States
Munster, Indiana, United States
Fortaleza, , Brazil
Nashville, Tennessee, United States
Perpignan, , France
Castro Valley, California, United States
Hyderabad, , India
Dallas, Texas, United States
Kasuga Shi, , Japan
Hyderbad, , India
Kirkland, Washington, United States
Ciudad Autonoma Buenos Aires, , Argentina
Herston, , Australia
Greensboro, North Carolina, United States
Hidaka, , Japan
Boise, Idaho, United States
Zagreb, , Croatia
Ho Chi Minh, , Vietnam
Ramat Gan, , Israel
Kota Bharu, , Malaysia
Toulouse Cedex 9, , France
Aguascalientes, , Mexico
Owosso, Michigan, United States
Zagreb, , Croatia
Shenyang, , China
Martin, , Slovakia
Bridgeton, Missouri, United States
Tonghua, , China
Houston, Texas, United States
Wels, , Austria
Plovdiv, , Bulgaria
Joinville, , Brazil
Lexington, Kentucky, United States
Baltimore, Maryland, United States
Vancouver, British Columbia, Canada
Jihlava, , Czechia
Sendai Shi, , Japan
Xian, , China
Yangzhou, , China
Chengdu, , China
Mesa, Arizona, United States
Burlingame, California, United States
Beer Sheva, , Israel
Portland, Oregon, United States
Erie, Pennsylvania, United States
Spokane, Washington, United States
Sao Jose Do Rio Preto, , Brazil
Morelia, , Mexico
Huhehaote, , China
Split, , Croatia
Vitoria, , Brazil
Dongguan, , China
Olomouc, , Czechia
Poitiers, , France
Goettingen, , Germany
Chennai, , India
Sacramento, California, United States
Kaili, , China
Wenzhou, , China
Bern, , Switzerland
Fukuoka, , Japan
London, , United Kingdom
Taunton, , United Kingdom
Erie, Pennsylvania, United States
Philadelphia, Pennsylvania, United States
Nashville, Tennessee, United States
Nashville, Tennessee, United States
Campinas, , Brazil
Los Alamitos, California, United States
Criciúma, , Brazil
Ijuí, , Brazil
São José Do Rio Preto, , Brazil
Las Condes, , Chile
Sacramento, California, United States
Coeur D'alene, Idaho, United States
Chicago, Illinois, United States
Springfield, Illinois, United States
Clinton Township, Michigan, United States
Farmington Hills, Michigan, United States
Flint, Michigan, United States
Hackensack, New Jersey, United States
Turku, , Finland
Budapest, , Hungary
Lueneburg, , Germany
Pavia, , Italy
Fukuoka Shi, , Japan
Kitakyushu Shi, , Japan
Suita Shi, , Japan
Hyderabad, , India
Brescia, , Italy
Seoul, , Korea, Republic Of
Aguascalientes, , Mexico
Culiacan, , Mexico
Tongaat, , South Africa
Wenzhou, , China
Tauranga, , New Zealand
Yichang, , China
Haifa, , Israel
Fullerton, California, United States
Bruxelles, , Belgium
Halifax, Nova Scotia, Canada
Québec, Quebec, Canada
Essen, , Germany
Faridabad, , India
Eger, , Hungary
Bialystok, , Poland
Boleslawiec, , Poland
Bydgoszcz, , Poland
Lublin, , Poland
Olsztyn, , Poland
Warszawa, , Poland
Sakarya, , Turkey
Novi Sad, , Serbia
Glendale, California, United States
Farmington Hills, Michigan, United States
New York, New York, United States
Mission Viejo, California, United States
Ishikawa, , Japan
Katowice Ochojec, , Poland
Rybnik, , Poland
Ankara, , Turkey
Elazıg, , Turkey
Distrito Federal, , Mexico
Frankfurt, , Germany
Istanbul, , Turkey
Safed, , Israel
Tulsa, Oklahoma, United States
Changsha, , China
Philadelphia, Pennsylvania, United States
Ijui, , Brazil
Burlingame, California, United States
Istanbul, , Turkey
Sao Paulo, , Brazil
São Paulo, , Brazil
Tianjin, , China
Chicago, Illinois, United States
Springfield, Illinois, United States
Sliven, , Bulgaria
Southfield, Michigan, United States
Taizhou, , China
Ostrava Vitkovice, , Czechia
Vaasa, , Finland
Berlin, , Germany
Sofia, , Bulgaria
Berlin, , Germany
Frankfurt, , Germany
Tsukuba City, , Japan
Seongnam Si, , Korea, Republic Of
Hull, , United Kingdom
Fulda, , Germany
Sheffield, , United Kingdom
Watford, , United Kingdom
Rouen Cedex, , France
Dresden, , Germany
Vila Nova De Gaia, , Portugal
Lueneburg, , Germany
Miami, Florida, United States
Barakaldo, , Spain
Berlin, , Germany
Shanghai, , China
Quincy, Illinois, United States
Detroit, Michigan, United States
Hackensack, New Jersey, United States
Ann Arbor, Michigan, United States
Coronel Suarez, , Argentina
Bonheiden, , Belgium
Eau Claire, Wisconsin, United States
Uberaba, , Brazil
Beijing, , China
Taiyuan, , China
Taizhou, , China
Bjelovar, , Croatia
Osijek, , Croatia
Praha 6, , Czechia
Bourg En Bresse Cedex, , France
Hamburg, , Germany
Idar Oberstein, , Germany
Leipzig, , Germany
Luebeck, , Germany
Liaocheng, , China
Schleswig, , Germany
Ulm, , Germany
Athens, , Greece
Ahmedabad, , India
Anand, , India
Bangalore, , India
Cochin, , India
Varanasi, , India
Haifa, , Israel
Salgotarjan, , Hungary
Petah Tikva, , Israel
Massa, , Italy
Kyoto Shi, , Japan
Kawasaki Shi, , Japan
Yantai, , China
Staszow, , Poland
Tokyo, , Japan
Shimotsuke, , Japan
Clearwater, Florida, United States
Augusta, Georgia, United States
Houston, Texas, United States
Coimbra, , Portugal
Spisska Nova Ves, , Slovakia
New Orleans, Louisiana, United States
Baltimore, Maryland, United States
Buenos Aires, , Argentina
Winchester, Virginia, United States
Braga, , Portugal
Ribeirao Preto, , Brazil
Linfen, , China
Jinan, , China
Ioannina, , Greece
Besançon Cedex, , France
Bordeaux Cedex, , France
Brest Cedex, , France
Caen, , France
Corbeil Essonnes Cedex, , France
Ibaraki, , Japan
Budapest, , Hungary
Gryfice, , Poland
Lund, , Sweden
Incheon, , Korea, Republic Of
Valencia, , Spain
Vigo, , Spain
Madrid, , Spain
Madrid, , Spain
Madrid, , Spain
Madrid, , Spain
Girona, , Spain
Lleida, , Spain
Palma De Mallorca, , Spain
Sandanski, , Bulgaria
Changhua, , Taiwan
Bangkoknoi, , Thailand
Pathum Wan, , Thailand
Airdrie, , United Kingdom
Bury, , United Kingdom
London, , United Kingdom
London, , United Kingdom
Luton, , United Kingdom
Truro, , United Kingdom
Uppsala, , Sweden
Basel, , Switzerland
Ha Noi, , Vietnam
Ho Chi Minh, , Vietnam
Lohr Am Main, , Germany
Riga, , Latvia
Vellore, , India
Hanoi, , Vietnam
Akron, Ohio, United States
Peoria, Illinois, United States
Parkville, , Australia
Traralgon, , Australia
Wels, , Austria
Springfield, Missouri, United States
Ruse, , Bulgaria
Sofia, , Bulgaria
Vina Del Mar, , Chile
Ostrava Vitkovice, , Czechia
Poruba, , Czechia
Glostrup, , Denmark
Sofia, , Bulgaria
Lille Cedex, , France
Limoges, , France
Metz Tessy, , France
Paris, , France
Paris, , France
Sofia, , Bulgaria
Aachen, , Germany
Poitiers, , France
Fulda, , Germany
Giessen, , Germany
Berlin, , Germany
Berlin, , Germany
Hamburg, , Germany
Lecco, , Italy
Milano, , Italy
Saitama Shi, , Japan
Shimonoseki Shi, , Japan
Suita Shi, , Japan
Anyang Si, , Korea, Republic Of
Busan, , Korea, Republic Of
Seoul, Ma, Korea, Republic Of
Dresden, , Germany
Seberang Jaya, , Malaysia
Seoul, , Korea, Republic Of
Ulsan, , Korea, Republic Of
Yongin Si, , Korea, Republic Of
Lodz, , Poland
Uden, , Netherlands
Auckland, , New Zealand
Covilha, , Portugal
Krakow, , Poland
Charlotte, North Carolina, United States
Austin, Texas, United States
Liege, , Belgium
Madrid, , Spain
Paris, , France
Shizuoka Aoi Ku, , Japan
Busan, , Korea, Republic Of
Vilnius, , Lithuania
Ciudad Autonoma Buenos Aires, , Argentina
Aix En Provence Cedex 01, , France
Trencin, , Slovakia
Bloemfontein, , South Africa
Rouen Cedex, , France
Ota Ku, , Japan
Olsztyn, , Poland
Chiangmai, , Thailand
Kansas City, Kansas, United States
Frankfurt, , Germany
Kitakyushu Shi, , Japan
Heidelberg, , Australia
South Brisbane, , Australia
Ath, , Belgium
Buffalo, New York, United States
Xiamen, , China
Clermont Ferrand Cedex, , France
Jamaica, New York, United States
Columbus, Ohio, United States
Grodzisk Mazowiecki, , Poland
Johannesburg, , South Africa
Terrassa, , Spain
Hamamatsu, , Japan
Shinjuku Ku, , Japan
Erlangen, , Germany
Zaragoza, , Spain
Pleven, , Bulgaria
Garches, , France
La Roche Sur Yon, , France
N T, , Hong Kong
Tokyo, , Japan
Uwajima Shi, , Japan
Adelaide, , Australia
Rybnik, , Poland
Goyang Si, , Korea, Republic Of
Daegu, , Korea, Republic Of
Omuta Shi, , Japan
Osaka Shi, , Japan
Seoul, , Korea, Republic Of
Niteroi, , Brazil
Dupnitsa, , Bulgaria
Leipzig, , Germany
Friedrichshafen, , Germany
Lueneburg, , Germany
Nai Mueang Subdistrict Mueang, , Thailand
Leszno, , Poland
Seoul, , Korea, Republic Of
Changchun, , China
Glasgow, , United Kingdom
Royal Oak, Michigan, United States
Cincinnati, Ohio, United States
Oklahoma City, Oklahoma, United States
Udine, , Italy
Wellington, , New Zealand
Ciudad De Mexico, , Mexico
Faridkot, , India
Lisboa, , Portugal
Davao City, , Philippines
Singapore, , Singapore
Bath, , United Kingdom
Murdoch, , Australia
Cordoba, , Argentina
Sherbrooke, Quebec, Canada
Torun, , Poland
Osaka, , Japan
Tokyo, , Japan
Muang, , Thailand
Neptune, New Jersey, United States
Buenos Aires, , Argentina
Montpellier, , France
Nancy, , France
Guimaraes, , Portugal
George, , South Africa
Seoul, , Korea, Republic Of
Krakow, , Poland
Varanasi, , India
Vizianagaram, , India
Jerusalem, , Israel
Samsun, , Turkey
Turkey, , Turkey
Philadelphia, Pennsylvania, United States
Sande, , Germany
Pretoria, , South Africa
Ankara, , Turkey
Erciyes, , Turkey
Istanbul, , Turkey
Jinan, , China
Bhubaneswar, , India
Koga, , Japan
Ipoh, , Malaysia
Konya, , Turkey
Guimaraes, , Portugal
Columbia, Missouri, United States
Ribeirao Preto, , Brazil
Xiangtan, , China
Hiroshima Shi, , Japan
Cape Town, , South Africa
Criciúma, , Brazil
Gorna Oryahovitsa, , Bulgaria
Jinzhou, , China
Kawasaki City, , Japan
Haskovo, , Bulgaria
Sindelfingen, , Germany
Rosario, , Argentina
Incheon, , Korea, Republic Of
Rostock, , Germany
Weimar, , Germany
Wuerzburg, , Germany
Larissa, , Greece
Tuebingen, , Germany
Thessaloniki, , Greece
Eger, , Hungary
Thessaloniki, , Greece
Pecs, , Hungary
Belgaum, , India
Bhubaneshwar, , India
Gurgaon, , India
Bikaner, , India
Chandigarh, , India
Pune, , India
Shimla, , India
Cagliari, , Italy
Higashihiroshima Shi, , Japan
Pavia, , Italy
Ota Ku, , Japan
Rozzano, , Italy
Seoul, , Korea, Republic Of
Hachioji, , Japan
Saga, , Japan
Kitakyushu Shi, , Japan
Hiroshima Shi, , Japan
Kobe Shi, , Japan
Gangseo Gu, , Korea, Republic Of
Seoul, , Korea, Republic Of
Burbank, California, United States
Joliet, Illinois, United States
Burnsville, Minnesota, United States
Edina, Minnesota, United States
Brandon, Manitoba, Canada
Minden, , Germany
Alexandroupolis, , Greece
Athens, , Greece
Larisa, , Greece
Gubbio, , Italy
Saitama Shi, , Japan
Sendai Shi, , Japan
Daegu, , Korea, Republic Of
Seoul, , Korea, Republic Of
Fukuoka Shi, , Japan
Seoul, , Korea, Republic Of
Seoul, , Korea, Republic Of
Chiayi, , Taiwan
Stoke On Trent, , United Kingdom
Gifu, , Japan
Himeji Shi, , Japan
Hiroshima, , Japan
Kagoshima, , Japan
Serdang, , Malaysia
Cebu, , Philippines
Staszow, , Poland
Porto, , Portugal
Brasov, , Romania
Bucuresti, , Romania
Bucuresti, , Romania
Manila, , Philippines
Manila, , Philippines
Manila, , Philippines
Pasay City, , Philippines
Boca Raton, Florida, United States
Timisoara, , Romania
Pasig City, , Philippines
Belgrade, , Serbia
Sombor, , Serbia
Subotica, , Serbia
Uzice, , Serbia
Trenton, New Jersey, United States
Houston, Texas, United States
Singapore, , Singapore
Alicante, , Spain
Badalona, , Spain
Somerset West, , South Africa
Barcelona, , Spain
L'hospitalet De Llobregat, , Spain
La Coruña, , Spain
Madrid, , Spain
Santiago De Compostela, , Spain
Sevilla, , Spain
Valencia, , Spain
Valladolid, , Spain
Skövde, , Sweden
Aarau, , Switzerland
Keelung, , Taiwan
New Taipei City, , Taiwan
Taipei, , Taiwan
Ho Chi Minh, , Vietnam
Ho Chi Minh, , Vietnam
Klang, , Malaysia
Lisboa, , Portugal
Saint Louis Park, Minnesota, United States
Medicine Hat, Alberta, Canada
Sudbury, Ontario, Canada
Altenburg, , Germany
Thessaloniki, , Greece
Bangkok, , Thailand
San Luis Potosi, , Mexico
Quezon City, , Philippines
Belgaum, , India
Pietra Ligure, , Italy
Quezon, , Philippines
Anyang, , China
Ganzhou, , China
Thane, , India
Toyohasi Shi, , Japan
Vancouver, British Columbia, Canada
Thessaloniki, , Greece
Brescia, , Italy
Otahuhu, , New Zealand
Trieste, , Italy
Busan, , Korea, Republic Of
La Coruña, , Spain
Douliou City, , Taiwan
Canton, Ohio, United States
Lianyungang, , China
Nanjing, , China
Botevgrad, , Bulgaria
Toronto, Ontario, Canada
Qingdao, , China
Seoul, , Korea, Republic Of
Besancon Cedex, , France
Essen, , Germany
Kolkata, , India
Timisoara, , Romania
Trebisov, , Slovakia
La Louvière, , Belgium
Budapest, , Hungary
Reggio Emilia, , Italy
Roma, , Italy
Chiba, , Japan
Sendai Shi, , Japan
Rajkot, , India
Perugia, , Italy
Maebashi, , Japan
Ina Shi, , Japan
Chennai, , India
Mumbai, , India
Mysuru, , India
Nishinomiya Shi, , Japan
Boleslawiec, , Poland
Bydgoszcz, , Poland
Santa Maria Da Feira, , Portugal
Belgrade, , Serbia
Madrid, , Spain
Kaohsiung, , Taiwan
Redwood City, California, United States
San Nicolas, , Argentina
Sumthana, , India
Delft, , Netherlands
Perugia, , Italy
Osaka, , Japan
Seoul, , Korea, Republic Of
Lodz, , Poland
Riga, , Latvia
Kuala Lumpur, , Malaysia
Barcelona, , Spain
Lisboa, , Portugal
Tucson, Arizona, United States
Nottingham, , United Kingdom
Danang, , Vietnam
Ho Chi Minh, , Vietnam
Hong Kong, , Hong Kong
Bhubaneswar, , India
Ciudad Autonoma Buenos Aires, , Argentina
Criciúma, , Brazil
Campinas, , Brazil
Melbourne, Victoria, Australia
Dazhou, , China
Dongguan, , China
Deyang, , China
Ganzhou, , China
Guangzhou, , China
Daegu, , Korea, Republic Of
Chartres Cedex, , France
Lisboa, , Portugal
Bad Neustadt, , Germany
Nové Zámky, , Slovakia
Zilina, , Slovakia
East London, , South Africa
Barcelona, , Spain
Mostoles, , Spain
Beijing, Beijing, China
Washington, District Of Columbia, United States
Cremona, , Italy
Roma, , Italy
San Martin, , Argentina
Clayton, , Australia
St. Gallen, , Switzerland
New Taipei City, , Taiwan
Southport, , Australia
Cheltenham, , United Kingdom
Exeter, , United Kingdom
Nanyang, , China
Leicester, , United Kingdom
Brno, , Czechia
Taian, , China
Wuhan, , China
Praha 2, , Czechia
Winnipeg, Manitoba, Canada
Greenfield Park, Quebec, Canada
Genova, , Italy
Matsubara Shi, , Japan
Seoul, , Korea, Republic Of
Poitiers, , France
Chennai, , India
Guwahati, , India
Mumbai, , India
Ankara, , Turkey
Hyderabad, , India
Warangal, , India
Tokyo, , Japan
Evanston, Illinois, United States
Bruxelles, , Belgium
Passo Fundo, , Brazil
Porto Alegre, , Brazil
Liaocheng, , China
Praha 5, , Czechia
Yanji, , China
Zhanjiang, , China
Ajmer, , India
La Crosse, Wisconsin, United States
Varazdin, , Croatia
Brno, , Czechia
Hastings, , New Zealand
Blagoevgrad, , Bulgaria
Xuzhou, , China
Hamburg, , Germany
Rotorua, , New Zealand
Rajathevi, , Thailand
Bialystok, , Poland
Springfield, Illinois, United States
Sao Paulo, , Brazil
Pisa, , Italy
Kurume Shi, , Japan
Wichita, Kansas, United States
Pleven, , Bulgaria
Calgary, Alberta, Canada
New Hyde Park, New York, United States
Box Hill, , Australia
Woolloongabba, , Australia
Guangzhou, , China
Hangzhou, , China
Jining, , China
Linyi, , China
Nanchong, , China
Xuancheng, , China
Porto Alegre, , Brazil
Berlin, , Germany
Heidelberg, , Germany
Potsdam, , Germany
Guwahati, , India
Kozhikode, , India
Lucknow, , India
L'aquila, , Italy
Chiba, , Japan
Kawasaki City, , Japan
Gwangju, , Korea, Republic Of
Yongin Si, , Korea, Republic Of
Kuching, , Malaysia
Manila, , Philippines
Belgrade, , Serbia
Porto Alegre, , Brazil
Sevilla, , Spain
Tarragona, , Spain
Göteborg, , Sweden
Taichung, , Taiwan
Sao Jose Do Rio Preto, , Brazil
Pazardzhik, , Bulgaria
Diyarbakir, , Turkey
Hanoi, , Vietnam
Liuzhou, , China
Aberdeen, , United Kingdom
Whittier, California, United States
Aguascalientes, , Mexico
Portland, Oregon, United States
Nashville, Tennessee, United States
San Miguel De Tucuman, , Argentina
Dartford, , United Kingdom
Cincinnati, Ohio, United States
Singapore, , Singapore
Doncaster, , United Kingdom
Suzhou, , China
Vijayawada, , India
Visakhapatnam, , India
London, , United Kingdom
Wakefield, , United Kingdom
Higashihiroshima Shi, , Japan
Jinan, , China
Seoul, , Korea, Republic Of
Kure, , Japan
Seoul, , Korea, Republic Of
Plymouth, , United Kingdom
Orlando, Florida, United States
Marikina City, , Philippines
La Coruña, , Spain
Malaga, , Spain
Jeju Special, , Korea, Republic Of
Johnson City, New York, United States
Rockville, Maryland, United States
Hangzhou, , China
Tupelo, Mississippi, United States
Sofia, , Bulgaria
Kingston, Ontario, Canada
Chicago, Illinois, United States
Boston, Massachusetts, United States
Omaha, Nebraska, United States
New York, New York, United States
Adelaide, South Australia, Australia
Camperdown, New South Wales, Australia
Herston, Queensland, Australia
Kingston, , Canada
Osorno, , Chile
Dundee, , United Kingdom
New Delhi, Delhi, India
Haifa, , Israel
Haifa, , Israel
Jerusalem, , Israel
Tel Aviv, , Israel
Seoul, , Korea, Republic Of
Seoul, , Korea, Republic Of
Seoul, , Korea, Republic Of
Auckland, , New Zealand
Manila, Ncr, Philippines
Tainan, , Taiwan
Taipei, , Taiwan
Tiwi, Northern Territory, Australia
Campina Grande Do Sul, , Brazil
Beijing, Beijing, China
Patients applied
Trial Officials
Janssen Research & Development, LLC Clinical Trial
Study Director
Janssen Research & Development, LLC
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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