A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE
Launched by JANSSEN RESEARCH & DEVELOPMENT, LLC · Jan 19, 2023
Trial Information
Current as of July 24, 2025
Recruiting
Keywords
ClinConnect Summary
The LIBREXIA-STROKE trial is studying a new medication called milvexian to see if it can help prevent another ischemic stroke in people who have recently experienced one or a high-risk transient ischemic attack (TIA), which is sometimes called a "mini-stroke." In this study, participants will be randomly assigned to receive either milvexian or a placebo (a substance with no active medication) to compare how well each option works.
To be eligible for this trial, participants must have had an ischemic stroke or a TIA within the last 48 hours and meet specific health criteria, such as having a certain level of neurological symptoms and being willing to follow the trial guidelines. Participants will be monitored closely and can expect to adhere to some lifestyle restrictions during the study. It's important to note that women in the study must not be pregnant or planning to become pregnant for a short time after the study medication. If you or a loved one are interested in participating, please talk to a healthcare provider for more information.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Ischemic Stroke: a neurological deficit attributable to an acute brain infarction and national institute of health stroke score scale (NIHSS) score less than or equal to (\<=) 7 and at least 1 of the following: persistent signs or symptoms of the ischemic event at the time of randomization, or acute, ischemic brain lesion determined by standard-of-care neuroimaging, or participant underwent thrombolysis or thrombectomy, or transient ischemic attack (TIA): acute onset neurological deficit attributable to focal ischemia of the brain by history or examination, with complete symptom resolution of the deficit and no brain infarction on neuroimaging (example, computed tomography (CT) scan or magnetic resonance imaging (MRI), performed as part of standard medical practice), and ABCD2 Score greater than or equal to (\>=) 6
- • Participants will be randomized as soon as possible after determining eligibility and within 48 hours of onset of event.
- • Current or planned antiplatelet treatment per international and/or local guidelines. If acetyl salicylic acid (ASA) is used, it will be limited to low dose (75 to 100 milligrams (mg)/day). Loading dose of antiplatelet agents (including ASA) are allowed per standard-of-care
- • A female participant must agree not to be pregnant, breastfeeding, or planning to become pregnant until 4 days (5 half lives) after the last dose of study intervention
- • Willing and able to adhere to the lifestyle restrictions specified in this protocol
- Exclusion Criteria:
- • Prior history of intracranial hemorrhage except subarachnoid hemorrhage greater than (\>) 1 year prior with adequate treatment
- • The index stroke or TIA is considered to have a cardio-embolic etiology based on local standard-of-care investigations and for which guidelines recommend anticoagulation
- • The index stroke or TIA considered to have another known cause, not related to athero-thrombotic sources (treatment of acute stroke trial \[TOAST\] Other Determined Etiology), based on local standard-of-care investigations
- • Increased risk of bleeding, including clinically significant bleeding within the previous 3 months or known bleeding diathesis or known activated partial thromboplastin time (aPTT) prolongation or spinal cord hemorrhage or retinal hemorrhage
- • Current active liver disease, eg, acute hepatitis, known cirrhosis, including participants receiving antiviral treatment for hepatitis
- • Known allergies, hypersensitivity, or intolerance to milvexian or its excipients
About Janssen Research & Development, Llc
Janssen Research & Development, LLC, a subsidiary of Johnson & Johnson, is a leading pharmaceutical company dedicated to advancing innovative therapies in multiple therapeutic areas, including oncology, immunology, neuroscience, infectious diseases, and cardiovascular health. With a strong commitment to scientific excellence and patient-centered research, Janssen leverages cutting-edge technology and collaborative partnerships to drive the development of transformative treatments. The company is focused on addressing unmet medical needs through rigorous clinical trials and a robust pipeline, aiming to improve health outcomes and enhance the quality of life for patients worldwide.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Chicago, Illinois, United States
Ann Arbor, Michigan, United States
New York, New York, United States
Saint Louis, Missouri, United States
Abington, Pennsylvania, United States
Boston, Massachusetts, United States
Copenhagen, , Denmark
Edina, Minnesota, United States
Adelaide, South Australia, Australia
Sudbury, Ontario, Canada
Sarasota, Florida, United States
East Lansing, Michigan, United States
Royal Oak, Michigan, United States
Edmonton, Alberta, Canada
Camden, New Jersey, United States
Baltimore, Maryland, United States
Chicago, Illinois, United States
Preston, , United Kingdom
Brooklyn, New York, United States
Burlingame, California, United States
Split, , Croatia
Philadelphia, Pennsylvania, United States
San Diego, California, United States
Portland, Oregon, United States
Thessaloniki, , Greece
Vancouver, British Columbia, Canada
Cincinnati, Ohio, United States
Houston, Texas, United States
Akron, Ohio, United States
Washington, District Of Columbia, United States
Omaha, Nebraska, United States
Nashville, Tennessee, United States
Paris, , France
Indianapolis, Indiana, United States
Portland, Oregon, United States
Paris, , France
Columbus, Ohio, United States
Christchurch, , New Zealand
Asheville, North Carolina, United States
Singapore, , Singapore
Sheffield, , United Kingdom
Louisville, Kentucky, United States
San Francisco, California, United States
Aurora, Colorado, United States
Portland, Oregon, United States
Peoria, Illinois, United States
East Kilbride, , United Kingdom
Seattle, Washington, United States
Singapore, , Singapore
Bangkok, , Thailand
Cleveland, Ohio, United States
Glendale, California, United States
Spokane, Washington, United States
Rozzano, , Italy
Mesa, Arizona, United States
Trenton, New Jersey, United States
Newark, Delaware, United States
Johnson City, New York, United States
Essen, , Germany
Hannover, , Germany
Parkville, , Australia
Melbourne, Victoria, Australia
Camperdown, New South Wales, Australia
Deggendorf, , Germany
Kortrijk, , Belgium
Aberdeen, , United Kingdom
Tupelo, Mississippi, United States
Olomouc, , Czechia
Ioannina, , Greece
Cheltenham, , United Kingdom
Lincoln, , United Kingdom
York, , United Kingdom
Tel Aviv, , Israel
Pensacola, Florida, United States
Kingston, Ontario, Canada
Plymouth, , United Kingdom
Nashville, Tennessee, United States
Manila, , Philippines
Nashville, Tennessee, United States
Winchester, Virginia, United States
Bath, , United Kingdom
Halifax, , United Kingdom
Uppsala, , Sweden
Boca Raton, Florida, United States
Jamaica, New York, United States
Wuerzburg, , Germany
Dundee, , United Kingdom
Kuala Lumpur, , Malaysia
Redwood City, California, United States
Breda, , Netherlands
Göteborg, , Sweden
Hamilton, , New Zealand
Hull, , United Kingdom
Haifa, , Israel
Taipei, , Taiwan
Leipzig, , Germany
Odense C, , Denmark
Leicester, , United Kingdom
Gent, , Belgium
Herlev, , Denmark
Tokyo, , Japan
Berlin, , Germany
Auckland, , New Zealand
Seoul, , Korea, Republic Of
Taipei, , Taiwan
Bronx, New York, United States
Turku, , Finland
Stockholm, , Sweden
Caen, , France
Eugene, Oregon, United States
Brussels, , Belgium
Leipzig, , Germany
Milano, , Italy
Haifa, , Israel
New York, New York, United States
Seoul, , Korea, Republic Of
Erie, Pennsylvania, United States
Dallas, Texas, United States
Adelaide, , Australia
Bethesda, Maryland, United States
Bruxelles, , Belgium
Austin, Texas, United States
Ramat Gan, , Israel
Zaragoza, , Spain
Paris, , France
Heidelberg, , Germany
Garches, , France
Leuven, , Belgium
Seoul, , Korea, Republic Of
New York, New York, United States
Augusta, Georgia, United States
Singapore, , Singapore
Oakland, California, United States
Jerusalem, , Israel
Dundee, , United Kingdom
Tallinn, , Estonia
Fukuoka, , Japan
Tainan, , Taiwan
La Louvière, , Belgium
Seoul, , Korea, Republic Of
Neptune, New Jersey, United States
Nitra, , Slovakia
Thessaloniki, , Greece
Norfolk, Virginia, United States
Wellington, , New Zealand
Greensboro, North Carolina, United States
Tucson, Arizona, United States
Minden, , Germany
Calgary, Alberta, Canada
Praha 4, , Czechia
Seoul, , Korea, Republic Of
Seoul, , Korea, Republic Of
Long Beach, California, United States
Tel Aviv, , Israel
San Diego, California, United States
New Delhi, , India
Auckland, , New Zealand
Berlin, , Germany
Berlin, , Germany
Petah Tikva, , Israel
Brno, , Czechia
Aarau, , Switzerland
Kumamoto, , Japan
Haifa, , Israel
Hamburg, , Germany
Santiago, , Chile
Basel, , Switzerland
Camperdown, , Australia
Woolloongabba, , Australia
Athens, , Greece
Bucuresti, , Romania
Sacramento, California, United States
Hyderabad, , India
Bangkoknoi, , Thailand
Hefei, , China
Nanjing, , China
Gwangju, , Korea, Republic Of
Montpellier, , France
St Leonards, , Australia
Evanston, Illinois, United States
Antwerpen, , Belgium
New Delhi, , India
Seoul, , Korea, Republic Of
Tainan, , Taiwan
Dendermonde, , Belgium
Muenster, , Germany
Zagreb, , Croatia
Lucknow, , India
Praha 10, , Czechia
L'aquila, , Italy
Roma, , Italy
Seongnam Si, , Korea, Republic Of
Salamanca, , Spain
Santiago De Compostela, , Spain
Taoyuan County, , Taiwan
Potsdam, , Germany
Ludhiana, , India
Vellore, , India
Berlin, , Germany
New Westminster, British Columbia, Canada
Vaasa, , Finland
Baguio City, , Philippines
Nis, , Serbia
Yantai, Shandong, China
Doncaster, , United Kingdom
Osaka, , Japan
Fullerton, California, United States
Gyor, , Hungary
London, , United Kingdom
Cordoba, , Argentina
Cordoba, , Argentina
Madrid, , Spain
Dortmund, , Germany
Chennai, , India
Hamburg, , Germany
Cordoba, , Argentina
Roma, , Italy
Fukuoka, , Japan
Kagoshima, , Japan
Taunton, , United Kingdom
Bonheiden, , Belgium
Praha 5, , Czechia
Wirral, , United Kingdom
Bern, , Switzerland
Brandon, Manitoba, Canada
Shijiazhuang, Hebei, China
Lexington, Kentucky, United States
Ulm, , Germany
Tokyo, , Japan
Spisska Nova Ves, , Slovakia
Herston, , Australia
Pleven, , Bulgaria
Miskolc, , Hungary
Cremona, , Italy
Manila, , Philippines
Izmir, , Turkey
Wels, , Austria
Tallinn, , Estonia
Erlangen, , Germany
Aachen, , Germany
New Orleans, Louisiana, United States
Olsztyn, , Poland
Jinan, , China
Budapest, , Hungary
Lund, , Sweden
Farmington Hills, Michigan, United States
Jerusalem, , Israel
Incheon, , Korea, Republic Of
Truro, , United Kingdom
Davao City, , Philippines
Clinton Township, Michigan, United States
Tartu, , Estonia
Liverpool, , Australia
Bucuresti, , Romania
Sarasota, Florida, United States
Bialystok, , Poland
Everett, Washington, United States
Pisa, , Italy
Pazardzhik, , Bulgaria
Safed, , Israel
Lisboa, , Portugal
Sherbrooke, Quebec, Canada
Thessaloniki, , Greece
Tokyo, , Japan
Beijing, Beijing, China
Dzialdowo, , Poland
Daegu, , Korea, Republic Of
Altenburg, , Germany
Edegem, , Belgium
Buenos Aires, , Argentina
St. Gallen, , Switzerland
Springfield, Missouri, United States
Pavia, , Italy
Larissa, , Greece
Lecce, , Italy
Shenyang, , China
Changchun, , China
Lisboa, , Portugal
Olomouc, , Czechia
Sao Paulo, , Brazil
Diyarbakir, , Turkey
Wels, , Austria
Marikina City, , Philippines
Seoul, , Korea, Republic Of
Shinjuku Ku, , Japan
Mons, , Belgium
Porto Alegre, , Brazil
Guangzhou, , China
Xuzhou, , China
Vila Nova De Gaia, , Portugal
Detroit, Michigan, United States
Beijing, , China
Pune, , India
Changsha, , China
Fort Wayne, Indiana, United States
Kistarcsa, , Hungary
Goettingen, , Germany
La Mesa, California, United States
Torrance, California, United States
Berlin, , Germany
Pune, , India
Riga, , Latvia
Gyeonggi Do, , Korea, Republic Of
New Taipei City, , Taiwan
Praha 2, , Czechia
Temuco, , Chile
Lipa City, , Philippines
Guangzhou, , China
Ho Chi Minh, , Vietnam
Buffalo, New York, United States
Omaha, Nebraska, United States
Seoul, , Korea, Republic Of
Delft, , Netherlands
Houston, Texas, United States
Mississauga, Ontario, Canada
Newark, New Jersey, United States
Novi Sad, , Serbia
Saga, , Japan
London, , United Kingdom
Vac, , Hungary
Seoul, , Korea, Republic Of
Manila, , Philippines
Quezon City, , Philippines
Hangzhou, , China
Qingdao, , China
Shijiazhuang, , China
Aguascalientes, , Mexico
Kaohsiung, , Taiwan
Kaohsiung, , Taiwan
Pasig City, , Philippines
Watford, , United Kingdom
Hong Kong, , Hong Kong
Changchun, Jilin, China
Grand Rapids, Michigan, United States
Quincy, Illinois, United States
Nottingham, , United Kingdom
Nanchang, , China
Busan, , Korea, Republic Of
Warszawa, , Poland
Hiroshima, , Japan
Turku, , Finland
Washington, District Of Columbia, United States
Rotorua, , New Zealand
Wenzhou, , China
Murdoch, , Australia
Braga, , Portugal
Tonghua, Jilin, China
Shenyang, Liaoning, China
Hanoi, , Vietnam
Stoke On Trent, , United Kingdom
La Crosse, Wisconsin, United States
Seoul, , Korea, Republic Of
Clayton, , Australia
Heidelberg, , Australia
Madrid, , Spain
Madrid, , Spain
Kyoto Shi, , Japan
Daegu, , Korea, Republic Of
Warszawa, , Poland
Budapest, , Hungary
Uzice, , Serbia
Haifa, , Israel
Fukuoka, , Japan
Tauranga, , New Zealand
Bradenton, Florida, United States
Cordoba, , Argentina
Mar Del Plata, , Argentina
Seoul, , Korea, Republic Of
Klang, , Malaysia
Staszow, , Poland
Cape Town, , South Africa
Airdrie, , United Kingdom
Dresden, , Germany
Tokyo, , Japan
Athens, , Greece
Rijeka, , Croatia
Iloilo City, , Philippines
Thessaloniki, , Greece
Philadelphia, Pennsylvania, United States
Glasgow, , United Kingdom
Ulsan, , Korea, Republic Of
Lueneburg, , Germany
Portland, Oregon, United States
Randwick, , Australia
Pecs, , Hungary
Ankara, , Turkey
Mendoza, , Argentina
Copenhagen Nv, , Denmark
Worcester, , South Africa
Charlotte, North Carolina, United States
Rostock, , Germany
Poitiers, , France
Luebeck, , Germany
Rennes Cedex 09, , France
Chattanooga, Tennessee, United States
Bern, , Switzerland
Belgrade, , Serbia
Changsha, , China
Xi'an, , China
Busan, , Korea, Republic Of
Berlin, , Germany
Belgrade, , Serbia
Lueneburg, , Germany
Metz Tessy, , France
Talcahuano, , Chile
Dresden, , Germany
Budapest, , Hungary
Sleepy Hollow, New York, United States
Herston, Queensland, Australia
Quezon, , Philippines
Dallas, Texas, United States
Morelia, , Mexico
Qingdao, , China
Gwangju, , Korea, Republic Of
Porto, , Portugal
Kansas City, Kansas, United States
Muang, , Thailand
Hanoi, , Vietnam
Zagreb, , Croatia
Loures, , Portugal
Kragujevac, , Serbia
Izmir, , Turkey
Budapest, , Hungary
Chandigarh, , India
Madrid, , Spain
Madrid, , Spain
Sabadell, , Spain
Valencia, , Spain
Verona, , Italy
Konya, , Turkey
Box Hill, , Australia
Poitiers, , France
Farmington Hills, Michigan, United States
Riga, , Latvia
Tiwi, Northern Territory, Australia
Changchun, , China
Lanzhou, , China
Tianjin, , China
Eger, , Hungary
Vilnius, , Lithuania
Springfield, Illinois, United States
Beijing, , China
Wenzhou, , China
Seoul, , Korea, Republic Of
Seoul, , Korea, Republic Of
Usti Nad Labem, , Czechia
Badalona, , Spain
Barcelona, , Spain
Caba, , Argentina
Plovdiv, , Bulgaria
Osaka, , Japan
Changhua, , Taiwan
Fukuoka, , Japan
Toyoake, , Japan
Tokyo, , Japan
Zagreb, , Croatia
West Palm Beach, Florida, United States
Nanyang, , China
Hidaka, , Japan
Ipoh, , Malaysia
Seoul, , Korea, Republic Of
Hyderabad, , India
Gurgaon, , India
Corbeil Essonnes Cedex, , France
Budapest, , Hungary
Jihlava, , Czechia
Sevilla, , Spain
Tuebingen, , Germany
Chikushino Shi, , Japan
Fukuoka Shi, , Japan
Nagasaki Shi, , Japan
Hachioji, , Japan
Hiroshima Shi, , Japan
Gurgaon, , India
Kobe Shi, , Japan
Springfield, Illinois, United States
Dongguan, , China
Yanji, , China
Klagenfurt, , Austria
Daegu, , Korea, Republic Of
Roma, , Italy
Plovdiv, , Bulgaria
Valencia, , Spain
Hastings, , New Zealand
Pune, , India
Hamamatsu, , Japan
New Lambton Heights, , Australia
Warszawa, , Poland
Burlingame, California, United States
Nashik, , India
Uden, , Netherlands
Alicante, , Spain
Barakaldo, , Spain
Barcelona, , Spain
Cordoba, , Spain
Seoul, , Korea, Republic Of
Dartford, , United Kingdom
Lueneburg, , Germany
L'hospitalet De Llobregat, , Spain
Palma De Mallorca, , Spain
Genova, , Italy
Goyang Si, , Korea, Republic Of
Udine, , Italy
Sofia, , Bulgaria
Aarhus, , Denmark
Rouen Cedex, , France
Istanbul, , Turkey
Seoul, , Korea, Republic Of
Whittier, California, United States
Pavia, , Italy
Wenzhou, , China
Besançon Cedex, , France
Sofia, , Bulgaria
Sofia, , Bulgaria
Timisoara, , Romania
Córdoba, , Argentina
Bjelovar, , Croatia
Liege, , Belgium
Girona, , Spain
Greeley, Colorado, United States
Ciudad De Buenos Aires, , Argentina
Bern, , Switzerland
Hatsukaichi, , Japan
Wichita, Kansas, United States
Pingxiang, , China
Bruxelles, , Belgium
Frankfurt, , Germany
Mostoles, , Spain
South Brisbane, , Australia
Ahmedabad, , India
New Delhi, , India
Sungai Buloh, , Malaysia
Pretoria, , South Africa
Terrassa, , Spain
Seoul, Ma, Korea, Republic Of
Osaka, , Japan
Incheon, , Korea, Republic Of
Monterrey, , Mexico
Vigo, , Spain
Giessen, , Germany
New Hyde Park, New York, United States
Aguascalientes, , Mexico
Guangzhou, , China
Larisa, , Greece
Brescia, , Italy
Barcelona, , Spain
Sevilla, , Spain
Zaragoza, , Spain
Le Kremlin Bicetre Cedex, , France
Shimotsuke, , Japan
Oklahoma City, Oklahoma, United States
Athens, , Greece
Miami, Florida, United States
El Paso, Texas, United States
Herning, , Denmark
Greenfield Park, Quebec, Canada
Lodz, , Poland
Passo Fundo, , Brazil
Xiamen, , China
Budapest, , Hungary
Bikaner, , India
Chennai, , India
Vijayawada, , India
Osaka Shi, , Japan
Lublin, , Poland
Guimarães, , Portugal
Santa Maria Da Feira, , Portugal
Arlon, , Belgium
Adelaide, , Australia
Bangkok, , Thailand
Liaocheng, , China
Dalian, Liaoning, China
Eau Claire, Wisconsin, United States
Wuhan, , China
Sao Paulo, , Brazil
Port Charlotte, Florida, United States
Ruse, , Bulgaria
Debrecen, , Hungary
Ciudad Autonoma De Buenos Aires, , Argentina
Fitzroy, , Australia
Blagoevgrad, , Bulgaria
Pingxiang, Jiangxi, China
Houston, Texas, United States
Hanoi, , Vietnam
Buenos Aires, , Argentina
Aguascalientes, , Mexico
Xiangtan, , China
Chia Yi City, , Taiwan
Nanyang, Henan, China
Bhubaneswar, , India
Bridgeton, Missouri, United States
Southport, , Australia
Rosario, , Argentina
Beijing, Beijing, China
San Miguel De Tucuman, , Argentina
Lisboa, , Portugal
Sakarya, , Turkey
Ijuí, , Brazil
Lleida, , Spain
Madrid, , Spain
Hualien, , Taiwan
Suita Shi, , Japan
Tsukuba City, , Japan
Aki Gun, , Japan
Lanzhou, , China
Budapest, , Hungary
Tonghua, , China
Santa Monica, California, United States
Kitakyushu Shi, , Japan
Toyota Shi, , Japan
Sombor, , Serbia
Nashik, , India
Pathum Wan, , Thailand
Beijing, , China
Dalian, , China
Hangzhou, , China
Uwajima Shi, , Japan
Friedrichshafen, , Germany
Ciudad Autonoma Buenos Aires, , Argentina
Frankfurt, , Germany
Ha Noi, , Vietnam
Mission Viejo, California, United States
Burnsville, Minnesota, United States
Thessaloniki, , Greece
Serdang, , Malaysia
Kingston, , Canada
Sliven, , Bulgaria
Santiago, , Chile
Hangzhou, , China
Yantai, , China
Chongqing, , China
Tatabanya, , Hungary
Criciúma, , Brazil
Ciudad De Mexico, , Mexico
Evanston, Illinois, United States
Ciudad Autonoma Buenos Aires, , Argentina
Stara Zagora, , Bulgaria
Liptovsky Mikulas, , Slovakia
Trencin, , Slovakia
Zilina, , Slovakia
Sofia, , Bulgaria
Bloemfontein, , South Africa
Toronto, Ontario, Canada
Cincinnati, Ohio, United States
Martin, , Slovakia
Ishikawa, , Japan
Maebashi, , Japan
Somerset West, , South Africa
Aichi, , Japan
Koga, , Japan
Ciudad De Mexico, , Mexico
Porto Alegre, , Brazil
Luton, , United Kingdom
Taizhou, , China
Malaga, , Spain
Tulsa, Oklahoma, United States
Omuta Shi, , Japan
Shimonoseki Shi, , Japan
East London, , South Africa
George, , South Africa
Shanghai, , China
Jinan, , China
Kawasaki Shi, , Japan
Mysuru, , India
La Coruña, , Spain
São Paulo, , Brazil
Thane, , India
Nanjing, , China
Ankara, , Turkey
Brasília, , Brazil
Niteroi, , Brazil
Huhehaote, , China
Exeter, , United Kingdom
Brno, , Czechia
Concepcion, , Chile
Fulda, , Germany
Genève, , Switzerland
New Taipei City, , Taiwan
Limoges, , France
Taichung, , Taiwan
Thiruvananthapuram, , India
Eger, , Hungary
São Paulo, , Brazil
Paris, , France
Rajkot, , India
Davao City, , Philippines
Chiangmai, , Thailand
Sao Paulo, , Brazil
Ahmedabad, , India
Bangalore, , India
São José Do Rio Preto, , Brazil
Linyi, , China
Sao Paulo, , Brazil
Campinas, , Brazil
Botucatu, , Brazil
Belo Horizonte, , Brazil
Ijui, , Brazil
Criciúma, , Brazil
Sao Jose Do Rio Preto, , Brazil
Curitiba, , Brazil
Ribeirao Preto, , Brazil
Nishinomiya Shi, , Japan
Changzhou, , China
Kisvarda, , Hungary
Hyderabad, , India
Jinan, Shandong, China
Los Alamitos, California, United States
Sacramento, California, United States
Thousand Oaks, California, United States
Clearwater, Florida, United States
Delray Beach, Florida, United States
Orlando, Florida, United States
Coeur D'alene, Idaho, United States
Glenview, Illinois, United States
Joliet, Illinois, United States
Rockford, Illinois, United States
Springfield, Illinois, United States
Pikeville, Kentucky, United States
Baltimore, Maryland, United States
Silver Spring, Maryland, United States
Boston, Massachusetts, United States
Flint, Michigan, United States
Owosso, Michigan, United States
Southfield, Michigan, United States
Saint Louis, Missouri, United States
Hackensack, New Jersey, United States
Lake Success, New York, United States
Canton, Ohio, United States
Allentown, Pennsylvania, United States
Erie, Pennsylvania, United States
Philadelphia, Pennsylvania, United States
Nashville, Tennessee, United States
Buenos Aires, , Argentina
Buenos Aires, , Argentina
Buenos Aires, , Argentina
Ciudad Autonoma Buenos Aires, , Argentina
Ciudad Autonoma Buenos Aires, , Argentina
Ciudad Autonoma Buenos Aires, , Argentina
Ciudad Autonoma De Buenos Airess, , Argentina
Cordoba, , Argentina
Coronel Suarez, , Argentina
Federal, , Argentina
Salta, , Argentina
San Martin, , Argentina
Launceston, , Australia
Modling, , Austria
Ath, , Belgium
Campina Grande Do Sul, , Brazil
Fortaleza, , Brazil
Joinville, , Brazil
Porto Alegre, , Brazil
Porto Alegre, , Brazil
Uberaba, , Brazil
Gorna Oryahovitsa, , Bulgaria
Haskovo, , Bulgaria
Montana, , Bulgaria
Pleven, , Bulgaria
Sofia, , Bulgaria
Sofia, , Bulgaria
Sofia, , Bulgaria
Lethbridge, Alberta, Canada
Las Condes, , Chile
Santiago, , Chile
Vina Del Mar, , Chile
Guangzhou, , China
Suzhou, , China
Osijek, , Croatia
Varazdin, , Croatia
Zabok, , Croatia
Chomutov, , Czechia
Ostrava Vitkovice, , Czechia
Poruba, , Czechia
Praha 6, , Czechia
Písek, , Czechia
ålborg, , Denmark
Hus, , Finland
Lappeenranta, , Finland
Aix En Provence Cedex 01, , France
Bordeaux Cedex, , France
Bourg En Bresse Cedex, , France
Brest Cedex, , France
La Roche Sur Yon, , France
Laquenexy, , France
Le Mans Cedex 9, , France
Lille Cedex, , France
Marseille Cedex 05, , France
Nancy, , France
Nice Cedex 1, , France
Perpignan, , France
Toulouse Cedex 9, , France
Bremen, , Germany
Guenzburg, , Germany
Hamburg, , Germany
Idar Oberstein, , Germany
Sindelfingen, , Germany
Alexandroupolis, , Greece
N.T., , Hong Kong
New Territories, , Hong Kong
Budapest, , Hungary
Dunaujvaros, , Hungary
Salgotarjan, , Hungary
Vac, , Hungary
Amritsar, , India
Anand, , India
Bangalore, , India
Belgaum, , India
Bhubaneshwar, , India
Bhubaneswar, , India
Cochin, , India
Coimbatore, , India
Guwahati, , India
Hyderabad, , India
Hyderabad, , India
Hyderbad, , India
Jaipur, , India
Kolkata, , India
Kozhikode, , India
Ludhiana, , India
Mangalore, , India
Mysore, , India
Surat, , India
Surat, , India
Varanasi, , India
Varanasi, , India
Beer Sheva, , Israel
Naharya, , Israel
Yerushalayim, , Israel
Brescia, , Italy
Cagliari, , Italy
Foligno, , Italy
Lecco, , Italy
Massa, , Italy
Modena, , Italy
Perugia, , Italy
Perugia, , Italy
Pietra Ligure, , Italy
Reggio Emilia, , Italy
Chiba Shi, , Japan
Chiba, , Japan
Fukuoka Shi, , Japan
Fukuoka, , Japan
Higashihiroshima Shi, , Japan
Himeji Shi, , Japan
Ina Shi, , Japan
Kasuga Shi, , Japan
Kasugai Shi, , Japan
Kitakyushu Shi, , Japan
Kobe Shi, , Japan
Kyoto Shi, , Japan
Matsubara Shi, , Japan
Nagano Shi, , Japan
Nagoya Shi, , Japan
Okayama Shi, , Japan
Osaka Shi, , Japan
Saitama Shi, , Japan
Sendai Shi, , Japan
Shimonoseki Shi, , Japan
Tokyo, , Japan
Toyohasi Shi, , Japan
Yonezawa Shi, , Japan
Vilnius, , Lithuania
Kota Bharu, , Malaysia
Kuala Lumpur, , Malaysia
Seberang Jaya, , Malaysia
Aguascalientes, , Mexico
Culiacan, , Mexico
Distrito Federal, , Mexico
Mexico, , Mexico
Puebla, , Mexico
Otahuhu, , New Zealand
Cebu, , Philippines
Manila, , Philippines
Pasay City, , Philippines
Boleslawiec, , Poland
Bydgoszcz, , Poland
Chelmie, , Poland
Grodzisk Mazowiecki, , Poland
Gryfice, , Poland
Katowice Ochojec, , Poland
Krakow, , Poland
Leszno, , Poland
Lodz, , Poland
Rybnik, , Poland
Skarzysko Kamienna, , Poland
Torun, , Poland
Wejherowo, , Poland
Coimbra, , Portugal
Pragal, , Portugal
Vila Real, , Portugal
Brasov, , Romania
Constanta, , Romania
Oradea, , Romania
Targu Mures, , Romania
Belgrade, , Serbia
Bratislava, , Slovakia
Kosice, , Slovakia
Levoca, , Slovakia
Lucenec, , Slovakia
Nové Zámky, , Slovakia
Petrzalka, , Slovakia
Tongaat, , South Africa
Albacete, , Spain
Tarragona, , Spain
Valladolid, , Spain
Malmoe, , Sweden
Skövde, , Sweden
Chiayi, , Taiwan
Keelung, , Taiwan
Nai Mueang Subdistrict Mueang, , Thailand
Rajathevi, , Thailand
Bury, , United Kingdom
Wakefield, , United Kingdom
Ho Chi Minh, , Vietnam
Ho Chi Minh, , Vietnam
Ho Chi Minh, , Vietnam
Ho Chi Minh, , Vietnam
Boise, Idaho, United States
Pingxiang, , China
Suita Shi, , Japan
Vancouver, British Columbia, Canada
Taizhou, , China
Zhanjiang, , China
Cordoba, , Argentina
San Nicolas, , Argentina
Dongguan, , China
Jining, , China
Taiyuan, , China
Yichang, , China
Gangseo Gu, , Korea, Republic Of
Sejong Si, , Korea, Republic Of
Kuching, , Malaysia
Ilocos Sur, , Philippines
Iloilo, , Philippines
Johannesburg, , South Africa
Bursa, , Turkey
Samsun, , Turkey
Rockville, Maryland, United States
Columbia, Missouri, United States
Cordoba, , Argentina
Anyang Si, , Korea, Republic Of
Yongin Si, , Korea, Republic Of
San Fernando, , Philippines
Fayetteville, Arkansas, United States
Berkeley, California, United States
Castro Valley, California, United States
Irvine, California, United States
Palo Alto, California, United States
Miami, Florida, United States
Miami, Florida, United States
Chicago, Illinois, United States
Munster, Indiana, United States
Detroit, Michigan, United States
Hackensack, New Jersey, United States
Paoli, Pennsylvania, United States
Nashville, Tennessee, United States
Nashville, Tennessee, United States
Austin, Texas, United States
Fort Worth, Texas, United States
Kirkland, Washington, United States
Bankstown, , Australia
Campbelltown, , Australia
Midland, , Australia
Campinas, , Brazil
Santiago, , Chile
Baoji, , China
Baotou, , China
Changchun, , China
Chenzhou, , China
Dalian, , China
Daqing, , China
Guangzhou, , China
Hangzhou, , China
Jiaozuo, , China
Jinzhou, , China
Linfen, , China
Nanchong, , China
Nanyang, , China
Qiqihaer, , China
Shandong, , China
Shenyang, , China
Tai'an, , China
Taiyuan, , China
Wuxi, , China
Chartres Cedex, , France
Clermont Ferrand Cedex, , France
Hamburg, , Germany
Lohr Am Main, , Germany
Sande, , Germany
Schleswig, , Germany
Weimar, , Germany
Shimla, , India
Trieste, , Italy
Gifu, , Japan
Hiroshima Shi, , Japan
Ibaraki, , Japan
Kitakyushu Shi, , Japan
Kure Shi, , Japan
Kurume Shi, , Japan
Ota Ku, , Japan
Shizuoka Aoi Ku, , Japan
Urayasu Shi, , Japan
Jeju Special, , Korea, Republic Of
Culiacan, , Mexico
San Luis Potosi, , Mexico
Covilha, , Portugal
Arad, , Romania
Bucuresti, , Romania
Subotica, , Serbia
Levice, , Slovakia
Tongaat, , South Africa
Margate, , United Kingdom
Liuzhou, , China
Manila, Ncr, Philippines
Linfen, Shanxi, China
Porto Alegre, , Brazil
Sao Jose Do Rio Preto, , Brazil
Torrance, California, United States
Osorno, , Chile
Traralgon, , Australia
Glostrup, , Denmark
Aix En Provence Cedex 01, , France
Seoul, , Korea, Republic Of
Lucenec, , Slovakia
La Coruña, , Spain
Istanbul, , Turkey
Lisboa, , Portugal
Belgaum, , India
Beijing, , China
Dazhou, , China
Ganzhou, , China
Liaocheng, , China
Nanyang, , China
Taian, , China
Komoro Shi, , Japan
Sendai Shi, , Japan
Sandanski, , Bulgaria
Besançon Cedex, , France
Limoges, , France
Besancon Cedex, , France
Temple Terrace, Florida, United States
Changsha, , China
Chengdu, , China
Jingdezhen, , China
Luoyang, , China
Shantou, , China
Laquenexy, , France
Bikaner, , India
Fukuoka Shi, , Japan
Kawasaki City, , Japan
Sapporo Shi, , Japan
Incheon, , Korea, Republic Of
Seoul, , Korea, Republic Of
Uijeongbu Si, , Korea, Republic Of
Xian, , China
Taizhou, , China
Joliet, Illinois, United States
Niteroi, , Brazil
Dupnitsa, , Bulgaria
Sofia, , Bulgaria
Changsha, , China
Jinan, , China
Ostrava Vitkovice, , Czechia
Rouen Cedex, , France
Dresden, , Germany
Frankfurt, , Germany
Fulda, , Germany
N T, , Hong Kong
Vila Nova De Gaia, , Portugal
Lucknow, , India
Thessaloniki, , Greece
Osaka, , Japan
Busan, , Korea, Republic Of
Lisboa, , Portugal
Nanjing, , China
Campo Largo, , Brazil
Criciúma, , Brazil
Ribeirao Preto, , Brazil
São Paulo, , Brazil
Botevgrad, , Bulgaria
Anyang, , China
Ganzhou, , China
Lianyungang, , China
Gubbio, , Italy
Kawasaki City, , Japan
Yongin Si, , Korea, Republic Of
Timisoara, , Romania
Trebisov, , Slovakia
Douliou City, , Taiwan
Ankara, , Turkey
Poitiers, , France
Vitoria, , Brazil
Chengdu, , China
Shenyang, , China
Yangzhou, , China
Vishakhapatnam, , India
Madrid, , Spain
Huhehaote, , China
Chicago, Illinois, United States
New Delhi, Delhi, India
Sacramento, California, United States
Dongguan, , China
Kaili, , China
Chennai, , India
London, , United Kingdom
Tsukuba City, , Japan
Salamanca, , Spain
Cordoba, , Spain
Chiangmai, , Thailand
Brasilia, , Brazil
Kunming, , China
Urumchi, , China
Wuxi, , China
Brest Cedex, , France
Kawasaki City, , Japan
Tokyo, , Japan
Manila, , Philippines
Guimaraes, , Portugal
Banska Bystrica, , Slovakia
St. Gallen, , Switzerland
Barcelona, , Spain
Burbank, California, United States
Saint Louis Park, Minnesota, United States
Medicine Hat, Alberta, Canada
Mumbai, , India
Gifu, , Japan
Kurume Shi, , Japan
Matsubara Shi, , Japan
Ota Ku, , Japan
Saitama Shi, , Japan
Sendai Shi, , Japan
Toyohasi Shi, , Japan
London, , United Kingdom
Tiwi, , Australia
Curitiba, , Brazil
Niagara Falls, Ontario, Canada
Muenchen, , Germany
Kumamoto, , Japan
Bialystok, , Poland
Malaga, , Spain
Visakhapatnam, , India
Higashihiroshima Shi, , Japan
Kure, , Japan
La Coruña, , Spain
Lisboa, , Portugal
Faridkot, , India
Kolkata, , India
Sumthana, , India
Vizianagaram, , India
Guimaraes, , Portugal
Sao Jose Do Rio Preto, , Brazil
Ajmer, , India
Guwahati, , India
Mumbai, , India
Tokyo, , Japan
Winnipeg, Manitoba, Canada
Warangal, , India
Olsztyn, , Poland
Houston, Texas, United States
Halifax, Nova Scotia, Canada
Québec, Quebec, Canada
Essen, , Germany
Faridabad, , India
Ishikawa, , Japan
Boleslawiec, , Poland
Bydgoszcz, , Poland
Katowice Ochojec, , Poland
Krakow, , Poland
Lublin, , Poland
Rybnik, , Poland
Staszow, , Poland
Warszawa, , Poland
Elazıg, , Turkey
Istanbul, , Turkey
Nishinomiya Shi, , Japan
Deyang, , China
Varanasi, , India
Chiba, , Japan
Ankara, , Turkey
Erciyes, , Turkey
Istanbul, , Turkey
Turkey, , Turkey
Danang, , Vietnam
Ho Chi Minh, , Vietnam
Durban, , South Africa
Praha 6, , Czechia
Xuancheng, , China
Chiba, , Japan
Bad Neustadt, , Germany
Patients applied
Trial Officials
Janssen Research & Development, LLC Clinical Trial
Study Director
Janssen Research & Development, LLC
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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