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Recruitment-to-inflation Ratio to Set Positive End-expiratory Pressure for Laparoscopic/Robotic Surgery: a Multicenter Study

Launched by AZIENDA OSPEDALIERA DI PERUGIA · Jan 19, 2023

Trial Information

Current as of July 22, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is looking at how a specific breathing technique, called positive end-expiratory pressure (PEEP), affects the way obese patients breathe during laparoscopic or robotic surgery. The goal is to see how PEEP can improve lung function in patients who need help with breathing while they are under anesthesia and have air introduced into their abdomen (a process known as pneumoperitoneum).

To participate in this study, you need to be an adult with obesity (a body mass index of 30 or more) and be scheduled for this type of surgery. However, if you have certain serious health issues, like severe heart problems or chronic lung diseases, you won't be able to join. If you do take part, you can expect to be monitored closely during your surgery to see how well your lungs are working with the PEEP technique. This study is currently looking for participants, so it's a chance to contribute to important research that could improve care for patients like you in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adult obese (body mass index ≥ 30 kg/m2) patients undergoing invasive mechanical ventilation for laparoscopic or robotic surgery with pneumoperitoneum will be enrolled, upon the acquisition of informed consent.
  • Exclusion Criteria:
  • Will be excluded all the patients with the following conditions: american society of anesthesiologists (ASA) score ≥ 4; severe cardiopathy, intracranial hypertension, tracheosthomy, previous cardio-thoracic surgery, pulmonary hypertrension, broncho-pleural fistula, pulmonary emphysema, pnumothorax, chronic respiratory failure, chronic obstructive pulmonary disease, pregnancy.

About Azienda Ospedaliera Di Perugia

Azienda Ospedaliera di Perugia is a leading healthcare institution in Italy, dedicated to providing high-quality medical care and advancing clinical research. With a strong emphasis on innovation and patient-centered approaches, the hospital engages in a wide range of clinical trials aimed at enhancing treatment methodologies and improving patient outcomes. The institution collaborates with various academic and research organizations, ensuring rigorous scientific standards and ethical practices in its research endeavors. Through its commitment to excellence in healthcare and research, Azienda Ospedaliera di Perugia plays a pivotal role in the advancement of medical science and the development of new therapies.

Locations

Perugia, Umbria, Italy, Italy

Perugia, , Italy

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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