MIH and Hypersensitivity in Children

Launched by UNIVERSITÀ DEGLI STUDI DI BRESCIA · Jan 21, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at how well a special dental treatment can help children with sensitive teeth caused by a condition called Molar Incisor Hypomineralization (MIH). The treatment involves using a mousse made from casein phosphopeptide and amorphous calcium phosphate (CPP-ACPF) along with a light therapy called photo-bio-modulation. The goal is to see if this combination can reduce tooth sensitivity in children aged 6 to 14 who have at least one affected tooth.

To participate in the trial, children must be between 6 and 14 years old and have at least one tooth with MIH that is sensitive. However, those with milk protein allergies, certain chronic diseases, or specific dental issues are not eligible. Participants will be randomly placed into one of three groups to receive different treatments, and they can expect to have their tooth sensitivity monitored throughout the study. This trial is currently recruiting, and it's a great opportunity for children experiencing dental discomfort to possibly find relief through this innovative approach.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • children 6-14 years old
• • having at least one MIH-affected tooth and MIH-associated hypersensitivity.
• Exclusion Criteria:
• • allergy to milk proteins
• • chronic diseases,
• • carious lesions on the sensitive teeth
• • restorations on the sensitive teeth
• • other enamel defects (fluorosis, amelogenesis/dentinogenesis imperfecta...)
• • presence of orthodontic appliance
• • recent anti-inflammatory or cortisone therapies
• • recent desensitizing treatments.