Effects of Aerobic Exercise on the Cerebral Arterial System, Cognitive, and Motor Function in Post-stroke Patients.
Launched by THE HONG KONG POLYTECHNIC UNIVERSITY · Jan 20, 2023
Trial Information
Current as of August 20, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how aerobic exercise, like treadmill walking and cycling, can help improve brain blood flow, thinking skills, and movement abilities in people who have had a stroke. The researchers want to see if these exercises can make a difference in the health of the blood vessels in the brain and in the overall recovery of stroke patients. They will compare the results of stroke survivors with a similar group of people who have not had a stroke to better understand the benefits of exercise.
To participate in this study, individuals must be at least 50 years old, Chinese, and have had a stroke more than six months ago, with mild to moderate disabilities that allow them to engage in exercise. Participants will be randomly assigned to one of three groups: a control group or one of two exercise groups. Over three months, they will take part in 30-minute exercise sessions three times a week. Throughout the study, researchers will assess changes in brain blood flow, thinking abilities, and movement skills using special ultrasound techniques and tests. This research could provide valuable insights into how exercise might help improve recovery for stroke patients.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Inclusion criteria post stroke group
- • 1. Post stroke adult patients of Chinese origin, who are 50 years old or above,
- • 2. Time of stroke onset \>6months (chronic),
- • 3. Mild to moderate disability to be able to undertake aerobic exercise training (treadmill and stationery cycling),
- • 4. Not participating in a structured aerobic exercise training.
- • 2. Inclusion criteria Non stroke group.
- • 1. Adults of Chinese origin who are 50 years old or above,
- • 2. No history of stroke or Transient Ischemic stroke (TIA).
- Exclusion Criteria:
- • 1. Exclusion criteria post- stroke group
- • 1. Non-Chinese nationals,
- • 2. Time of stroke onset\<6months,
- • 3. Below 50 years of age,
- • 4. Currently participating in a structured aerobic exercise training,
- • 5. Cannot perform treadmill walking or stationery cycling, and
- • 6. Allergic to ultrasound gel.
- • 2. Exclusion criteria Non-stroke group.
- • 1. History of stroke or TIA.,
- • 2. Non-Chinese nationals,
- • 3. Below 50 years of age, and
- • 4. Allergic to ultrasound gel.
About The Hong Kong Polytechnic University
The Hong Kong Polytechnic University (PolyU) is a leading institution in applied research and education, dedicated to advancing knowledge and innovation in various fields, including health sciences. As a clinical trial sponsor, PolyU focuses on conducting rigorous and ethically sound research to enhance understanding of medical interventions and improve patient outcomes. The university leverages its multidisciplinary expertise, state-of-the-art facilities, and collaboration with industry partners to facilitate groundbreaking studies that address pressing health challenges. Committed to fostering an environment of academic excellence, PolyU aims to translate research findings into practical solutions that benefit society and contribute to the global advancement of healthcare.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Kowloon, , Hong Kong
Patients applied
Trial Officials
Michael TC Ying, PhD
Principal Investigator
The Hong Kong Polytechnic University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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