Visual Processing Speed and Objective Analysis of Ocular Movements in Multiple Sclerosis

Launched by INSTITUTO UNIVERSITARIO DE OFTALMOBIOLOGÍA APLICADA (INSTITUTE OF APPLIED OPHTHALMOBIOLOGY) - IOBA · Jan 20, 2023

Keywords

ClinConnect Summary

Anamnesis, ophthalmological medical history including difficulties in reading with appropriate glasses.

The following protocol will be applied:

* Comprehensive eye examination
* Stereopsis
* Primary gaze position
* Cover test: far and near
* Vergence and version eye movements
* Presence of nystagmus
* Far and near best corrected visual acuity, with updated refraction

-.Pupillary light reflex
* Biomicroscopy of the anterior pole
* Intraocular pressure
* Recording of eye movements during two standardized tests: International Reading Speed Texts test (IReST®) and Developmental Eye Movemen...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Diagnosis of Multiple Sclerosis
• • Best distant corrected visual acuity equal or greater than 0.7 (decimal scale). Glasses or soft contact lenses users.
• • Best close corrected visual acuity equal to or greater than 20/30 (Snellen scale).Glasses or soft contact lenses users.
• Exclusion Criteria:
• • Patients with a history of acute optic neuritis (ON) and/or who experienced an episode of ON \<6 months prior to the study, to avoid potential interference of papilledema with accurate peripapillary RNFL thickness measurements.
• • Patients with other retinal and optic nerve diseases, advanced cataracts according to the international Lens Opacities Classification System III (LOCS III) (opacities greater than C2N2)
• • Patients with other ophthalmological diseases that could affect central visual acuity
• • Subjects with high refractive error (+ - 6 diopters).
• • Subjects with other demyelinating disorders (neuromyelitis optica or acute disseminated encephalomyelitis).