Use of Indocyanine Green in Acute Cholecystitis

Launched by CORPORACION PARC TAULI · Jan 30, 2023

Keywords

ClinConnect Summary

This clinical trial is studying the use of a special dye called indocyanine green during surgery for a condition known as acute cholecystitis, which is an inflammation of the gallbladder. The goal is to see if using this dye can help doctors find and avoid damaging the bile ducts, which are important tubes that carry bile from the liver to the intestines. By improving visibility during the surgery, the researchers hope to decrease the overall time spent in surgery and reduce the chances of needing to switch to a more complicated open surgery.

To participate in the trial, individuals must be over 18 years old and have been advised to undergo urgent laparoscopic cholecystectomy (a minimally invasive surgery to remove the gallbladder) due to acute cholecystitis. However, certain people are not eligible, including those who are pregnant, have severe kidney issues, or have allergies to the dye. Participants will be randomly assigned to either receive the dye before surgery or to have the usual procedure without it. This study is being conducted at the Parc Taulí University Hospital in Sabadell, and it aims to make gallbladder surgery safer and more efficient for patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with an indication for urgent laparoscopic cholecystectomy due to acute cholecystitis regardless of its etiology.
• • Age over 18 years.
• • Patients who have read the study information sheet and signed the informed consent sheet.
• Exclusion Criteria:
• • Pregnant or breastfeeding patients.
• • Grade IV renal failure or patients on dialysis
• • Patients with previous hypersensitivity to indocyanine green
• • Patients with allergy to iodinated contrast
• • Patients with clinical hyperthyroidism, autonomic thyroid adenomas, and focal and diffuse autonomic abnormalities of the thyroid gland
• • Contraindication to laparoscopic surgery.
• • Suspicion of choledocholithiasis
• • Pediatric patients under 18 years of age.
• • Patients who refused to participate in the study